RERG blocking peptide
RERG Peptide - C-terminal region
Target Description: The function of Apbb1ip remains unknown.
NCBI and Uniprot Product Information
NCBI Description
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]
Uniprot Description
RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, monomeric; G protein; G protein, monomeric, Ras
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: membrane; cytosol; nucleus
Molecular Function: GTPase activity; GDP binding; GTP binding; estrogen receptor binding
Biological Process: negative regulation of cell proliferation; metabolic process; small GTPase mediated signal transduction; response to hormone stimulus; negative regulation of cell growth
Research Articles on RERG
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Product Notes
The RERG rerg (Catalog #AAA3239383) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The RERG Peptide - C-terminal region reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RERG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RERG rerg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PPREEFNFSV GFKDLNESLN ALEDQDLDAL MADLVADISE AEQRTIQAQK. It is sometimes possible for the material contained within the vial of "RERG, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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