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Testing Data (Image: Western blot of rat adrenal medulla. As shown in the autoradiograph, the antibody is specific for the ~55k DDC protein.)

anti-Rat DOPA Decarboxylase Antibody | anti-Ddc antibody

Rabbit Polyclonal Anti-DOPA Decarboxylase Antibody

Gene Names
Ddc; 5-HT; AADC; CG10697; ddc; DDC; DdcDm; DmelCG10697; fDDC; l(2)37Bl; l(2)37Ch; l(2)k02104
Reactivity
Rat
Applications
Western Blot
Synonyms
DOPA Decarboxylase; Rabbit Polyclonal Anti-DOPA Decarboxylase Antibody; anti-Ddc antibody
Ordering
For Research Use Only!
Reactivity
Rat
Form/Format
Protein G Purified - Liquid
Sequence Length
475
Applicable Applications for anti-Ddc antibody
Western Blot (WB)
Type Info
Mouse IgG
Immunogen
SDS denatured, recombinant bovine aromatic DOPA decarboxylase (DDC) expressed in E Coli and purified from inclusion bodies.

Testing Data

(Image: Western blot of rat adrenal medulla. As shown in the autoradiograph, the antibody is specific for the ~55k DDC protein.)

Testing Data (Image: Western blot of rat adrenal medulla. As shown in the autoradiograph, the antibody is specific for the ~55k DDC protein.)
Related Product Information for anti-Ddc antibody
Dopa decarboxylase (DDC), also known as AADC, is a homodimeric vitamin B6-dependent enzyme that catalyzes the decarboxylation of hydroxylated aromatic amino acids. DDC is expressed in the adrenal medulla and catecholaminergic neurons. It catalyzes the final step in the synthesis of the neurotransmitters dopamine and serotonin. Defects in DDC are associated with the development of schizophrenia, Parkinson's disease, and hypertension. Human DDC shares 89% aa sequence identity with mouse and rat DDC.
Product Categories/Family for anti-Ddc antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,863 Da
NCBI Official Full Name
dopa decarboxylase, isoform D
NCBI Official Synonym Full Names
Dopa decarboxylase
NCBI Official Symbol
Ddc
NCBI Official Synonym Symbols
5-HT; AADC; CG10697; ddc; DDC; DdcDm; DmelCG10697; fDDC; l(2)37Bl; l(2)37Ch; l(2)k02104
NCBI Protein Information
CG10697 gene product from transcript CG10697-RB
UniProt Protein Name
Aromatic-L-amino-acid decarboxylase
UniProt Gene Name
Ddc
UniProt Synonym Gene Names
AADC; DDC
UniProt Entry Name
DDC_DROME

Uniprot Description

Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span.

Research Articles on Ddc

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Product Notes

The Ddc ddc (Catalog #AAA555121) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal Anti-DOPA Decarboxylase Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DOPA Decarboxylase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Ddc ddc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOPA Decarboxylase, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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