Probable arginine--tRNA ligase, mitochondrial (RARS2) Recombinant Protein | RARS2 recombinant protein

Recombinant Human Probable arginine--tRNA ligase, mitochondrial (RARS2)

Cat. Num. AAA1323587

• Gene Names: RARS2; PCH6; ArgRS; RARSL; DALRD2; PRO1992
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable arginine--tRNA ligase; mitochondrial (RARS2); Recombinant Human Probable arginine--tRNA ligase; RARS2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 17-578, Full length protein
• Sequence: LNLPPENLITSISAVPISQKEEVADFQLSVDSLLEKDNDHSRPDIQVQAKRLAEKLRCDTVVSEISTGQRTVNFKINRELLTKTVLQQVIEDGSKYGLKSELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVIRINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEAADDKSVAKAAQEFFQRLELGDVQALSLWQKFRDLSIEEYIRVYKRLGVYFDEYSGESFYREKSQEVLKLLESKGLLLKTIKGTAVVDLSGNGDPSSICTVMRSDGTSLYATRDLAAAIDRMDKYNFDTMIYVTDKGQKKHFQQVFQMLKIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEIQLRMLQNMASIKTTKELKNPQETAERVGLAALIIQDFKGLLLSDYKFSWDRVFQSRGDTGVFLQYTHARLHSLEETFGCGYLNDFNTACLQEPQSVSILQHLLRFDEVLYKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQIKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPVCRM
• Sequence Length: 562

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RARS2 recombinant protein

This protein is an arginyl-tRNA synthetase that is found in the mitochondrial matrix. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6).

NCBI and Uniprot Product Information

• NCBI GI #: 197100773
• NCBI GeneID: 57038
• NCBI Accession #: NP_064716.2
• NCBI GenBank Nucleotide #: NM_020320.4
• UniProt Accession #: Q5T160; Q96FU5; Q9H8K8; B2RDT7
• Molecular Weight: 65,505 Da
• NCBI Official Full Name: probable arginine--tRNA ligase, mitochondrial isoform 1
• NCBI Official Synonym Full Names: arginyl-tRNA synthetase 2, mitochondrial
• NCBI Official Symbol: RARS2
• NCBI Official Synonym Symbols: PCH6; ArgRS; RARSL; DALRD2; PRO1992
• NCBI Protein Information: probable arginine--tRNA ligase, mitochondrial
• UniProt Protein Name: Probable arginine--tRNA ligase, mitochondrial
• Protein Family: Probable arginine--tRNA ligase
• UniProt Gene Name: RARS2
• UniProt Synonym Gene Names: RARSL; ArgRS

NCBI Description

This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]