Western Blot (WB)
(Western Blot analysis of extracts of various cells, using RARS2 antibody.)
Rabbit anti-Human, Mouse RARS2 Polyclonal Antibody | anti-RARS2 antibody
RARS2 Polyclonal Antibody
IHC: 1:50-1:200
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using RARS2 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using RARS2 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded mouse stomach using RARS2 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded mouse stomach using RARS2 antibody at dilution of 1:100 (x40 lens).)
NCBI and Uniprot Product Information
NCBI Description
This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Uniprot Description
RARS2: Defects in RARS2 are the cause of pontocerebellar hypoplasia type 6 (PCH6); also known as fatal infantile encephalopathy with mitochondrial respiratory chain defects. Pontocerebellar hypoplasia (PCH) is a heterogeneous group of disorders characterized by an abnormally small cerebellum and brainstem. Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein type: Aminoacyl-tRNA synthetase; EC 6.1.1.19; Ligase; Mitochondrial; Translation; Translation regulation
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: arginine-tRNA ligase activity; ATP binding; RNA binding
Biological Process: arginyl-tRNA aminoacylation; mitochondrial translation; tRNA aminoacylation for protein translation
Disease: Pontocerebellar Hypoplasia, Type 6
Research Articles on RARS2
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Product Notes
The RARS2 rars2 (Catalog #AAA3009231) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RARS2 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RARS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the RARS2 rars2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RARS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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