Human RAN binding protein 9 ELISA Kit | RANBP9 elisa kit
Human Ran-binding protein 9, RANBP9 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]
Uniprot Description
RANBP9: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. Belongs to the RANBP9/10 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; GAPs; GAPs, Ras; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 6p23
Cellular Component: microtubule associated complex; nucleus; cytosol
Molecular Function: protein binding; enzyme binding; Ran GTPase binding
Biological Process: axon guidance; protein complex assembly; microtubule nucleation
Research Articles on RANBP9
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Product Notes
The Human RANBP9 ranbp9 (Catalog #AAA9323148) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323148 ELISA Kit recognizes Human RANBP9. It is sometimes possible for the material contained within the vial of "RAN binding protein 9, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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