Rat v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) ELISA Kit | RALB elisa kit
Rat Ras-related protein Ral-B, RALB ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
putative GTP binding protein [RGD, Feb 2006]
Uniprot Description
RALB: Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. Interacts with EXOC2 and EXOC8. Interacts with RALBP1 via its effector domain. Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase- activating protein (GAP). Belongs to the small GTPase superfamily. Ras family.
Protein type: G protein, monomeric; G protein, monomeric, Ras; G protein
Cellular Component: exocyst; plasma membrane; autophagic vacuole; midbody; cytosol
Molecular Function: GTPase activity; GDP binding; GTP binding; ubiquitin protein ligase binding; ATPase binding
Biological Process: regulation of exocyst localization; positive regulation of protein binding; apoptosis; metabolic process; regulation of exocyst assembly; Ras protein signal transduction; positive regulation of protein amino acid phosphorylation; cellular response to starvation; negative regulation of protein binding
Research Articles on RALB
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Product Notes
The Rat RALB ralb (Catalog #AAA9323219) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323219 ELISA Kit recognizes Rat RALB. It is sometimes possible for the material contained within the vial of "v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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