Western Blot (WB)
(Western Blot: Sample: Recombinant CCK, Mouse.)
Rabbit anti-Mouse Cholecystokinin (CCK) Antibody | anti-CCK antibody
Polyclonal Antibody to Cholecystokinin (CCK)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Recombinant CCK, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CCK, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Stomach Tissue.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Homozygous knockout mice for this gene exhibit impaired insulin secretion, enhanced insulin sensitivity, and resistance to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Uniprot Description
CCK: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. Belongs to the gastrin/cholecystokinin family.
Protein type: Cell development/differentiation; Hormone; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9 72.43 cM|9 F4
Cellular Component: axon; axon hillock; cell soma; dendrite; extracellular region; extracellular space; perikaryon; terminal bouton
Molecular Function: hormone activity; neuropeptide hormone activity; protein binding
Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptosis; axonogenesis; behavioral fear response; eating behavior; negative regulation of appetite; neuron migration; positive regulation of apoptosis; positive regulation of cell proliferation; positive regulation of glutamate secretion; positive regulation of mitochondrial depolarization; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein oligomerization; protein kinase C-activating G-protein coupled receptor signaling pathway; regulation of sensory perception of pain; release of cytochrome c from mitochondria
Research Articles on CCK
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Product Notes
The CCK cck (Catalog #AAA2002701) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Cholecystokinin (CCK) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Cholecystokinin (CCK) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CCK cck for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cholecystokinin (CCK), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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