Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Mouse Spleen Tissue using TLR8 Polyclonal antibody)
Rabbit IgG TLR8 Antibody | anti-TLR8 antibody
TLR8
Gene Names
TLR8; CD288
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TLR8; anti-TLR8 antibody
Host
Rabbit IgG
Reactivity
Human, Mouse, Rat
Specificity
The antibody detects endogenous TLR8 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
PBS, pH 7.4, containing 0.5 BSA, 0.02% sodium azide as preservatives and 50% Glycerol.
Applicable Applications for anti-TLR8 antibody
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IF: 1:50-200
IHC: 1:200-500
WB: 1:200~1,100
IHC: 1:200-500
WB: 1:200~1,100
Immunogen
Recombinant fragment corresponding to 568-721aa of human TLR8.
Subcellular Location
Golgi membrane, endoplasmic reticulum membrane, endosome membrane, integral component of membrane, endolysosome membrane.
Expression
Liver, PCR rescued clones, placenta.
Preparation and Storage
Store -20°C.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Mouse Spleen Tissue using TLR8 Polyclonal antibody)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Mouse Spleen Tissue using TLR8 Polyclonal antibody)
Related Product Information for anti-TLR8 antibody
Homo sapiens toll-like receptor 8, mRNA
References
Ishii N, Funami K, Tatematsu M. et al. Endosomal localization of TLR8 confers distinctive proteolytic processing on human myeloid cells. J Immunol. 193(10):5118-28 (2014)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Homo sapiens toll-like receptor 8, mRNA
NCBI Official Synonym Full Names
toll like receptor 8
NCBI Official Symbol
TLR8
NCBI Official Synonym Symbols
CD288
NCBI Protein Information
toll-like receptor 8
Protein Family
NCBI Description
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]
Research Articles on TLR8
Similar Products
Product Notes
The TLR8 (Catalog #AAA8561062) is an Antibody produced from Rabbit IgG and is intended for research purposes only. The product is available for immediate purchase. The TLR8 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TLR8 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). IF: 1:50-200 IHC: 1:200-500 WB: 1:200~1,100. Researchers should empirically determine the suitability of the TLR8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR8, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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