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Western Blot (WB) (Western blot analysis of Jurkat cell lysate using GATA2 antibody.)

Rabbit GATA2 Antibody | anti-GATA2 antibody

GATA2 Antibody

Gene Names
GATA2; DCML; IMD21; NFE1B; MONOMAC
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purification
Synonyms
GATA2; GATA2 Antibody; FLJ45948; MGC2306; NFE1B; anti-GATA2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Purity/Purification
Affinity purification
Sequence Length
480
Applicable Applications for anti-GATA2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Recombinant protein of human GATA2
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Jurkat cell lysate using GATA2 antibody.)

Western Blot (WB) (Western blot analysis of Jurkat cell lysate using GATA2 antibody.)
Related Product Information for anti-GATA2 antibody
The zinc finger transcription factor GATA-2 is widely expressed and plays an essential role in many developmental processes (1). Studies on GATA-2 knockout mice indicate that this protein is required in hematopoiesis (2). GATA-2 also inhibits the differentiation of white (3) and brown adipocytes (4) and has been shown to suppress the proliferation of neuronal progenitor cells (5).
References
20. Tong, Q. et al. (2003) Drug News Perspect. 16, 585-588. 21. Tsai, F.Y. et al. (1994) Nature 371, 221-226. 22. Tong, Q. et al. (2005) Mol. Cell. Biol. 25, 706-715. 23. Tsai, J. et al. (2005) EMBO Rep. 6, 879-884. 24. El Wakil, A. et al. (2006) Development 133, 2155-2165.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49kDa
NCBI Official Full Name
endothelial transcription factor GATA-2 isoform 1
NCBI Official Synonym Full Names
GATA binding protein 2
NCBI Official Symbol
GATA2
NCBI Official Synonym Symbols
DCML; IMD21; NFE1B; MONOMAC
NCBI Protein Information
endothelial transcription factor GATA-2
UniProt Protein Name
Endothelial transcription factor GATA-2
Protein Family
UniProt Gene Name
GATA2

NCBI Description

This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Uniprot Description

Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.

Research Articles on GATA2

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Product Notes

The GATA2 gata2 (Catalog #AAA8505296) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GATA2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GATA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GATA2 gata2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GATA2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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