Rabbit Leptin receptor gene-related protein (LEPROT) ELISA Kit | LEPROT elisa kit
Rabbit Leptin receptor gene-related protein (LEPROT) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]
Uniprot Description
LEPROT: Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. Belongs to the OB-RGRP/VPS55 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: Golgi membrane; Golgi apparatus; integral to membrane; endosome membrane; endosome
Molecular Function: receptor binding
Biological Process: negative regulation of JAK-STAT cascade
Research Articles on LEPROT
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Product Notes
The Rabbit LEPROT leprot (Catalog #AAA7243434) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7243434 ELISA Kit recognizes Rabbit LEPROT. It is sometimes possible for the material contained within the vial of "Leptin receptor gene-related protein (LEPROT), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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