Rabbit cADPRH/CD38 ELISA Kit | cADPRH/CD38 elisa kit
Rabbit cADPRH/CD38 (Cyclic ADP Hydrolase) ELISA Kit
Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rabbit cADPRH/CD38. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Rabbit cADPRH/CD38 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rabbit cADPRH/CD38, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzymesubstrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rabbit cADPRH/CD38. You can calculate the concentration of Rabbit cADPRH/CD38 in the samples by comparing the OD of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq, Jul 2008]
Uniprot Description
CD38: Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Belongs to the ADP-ribosyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Cell surface; EC 3.2.2.6; Hydrolase; EC 2.4.99.20; Membrane protein, integral; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Cell cycle regulation; Lyase
Chromosomal Location of Human Ortholog: 4p15
Cellular Component: cell surface; membrane; plasma membrane; integral to membrane; nucleus
Molecular Function: transferase activity; phosphorus-oxygen lyase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity
Biological Process: response to drug; response to retinoic acid; metabolic process; positive regulation of transcription, DNA-dependent; positive regulation of insulin secretion; female pregnancy; signal transduction; positive regulation of cell growth; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; B cell receptor signaling pathway; response to hydroperoxide; response to hypoxia; positive regulation of vasoconstriction; positive regulation of B cell proliferation; negative regulation of transcription, DNA-dependent; response to progesterone stimulus; negative regulation of bone resorption; negative regulation of apoptosis
Research Articles on cADPRH/CD38
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Product Notes
The Rabbit cADPRH/CD38 cd38 (Catalog #AAA2515604) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2515604 ELISA Kit recognizes Rabbit cADPRH/CD38. It is sometimes possible for the material contained within the vial of "cADPRH/CD38, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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