Testing Data
(Image: c-KIT staining of rat skin (epidermis). c-KIT detection was done using anti-rabbit Cy3 conjugated antibodies (red color). DAPI was used to counterstain cell nuclei (blue color).Working dilution: 1:100-1:300.)
Rabbit c-Kit Antibody | anti-c-Kit/CD117 antibody
c-Kit, Affinity Purified Antibody, Rabbit
Gene Names
Oprl1; ORL
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Synonyms
c-Kit; Affinity Purified Antibody; Rabbit; anti-c-Kit/CD117 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form/Format
PBS containing 0.05% sodium azide.
Sequence
TASSSQPLLVHDDV
Sequence Length
367
Applicable Applications for anti-c-Kit/CD117 antibody
Immunohistochemistry (IHC)
Application Notes
IHC 1:100-1:400
Dilutions listed as a recommendation.
Other dilutions should be determined by investigator.
Dilutions listed as a recommendation.
Other dilutions should be determined by investigator.
Product Type
Whole Serum
Preparation and Storage
Maintain at +2-8°C for 3 months or at -20°C for longer periods.
Stable for 1 year.
Avoid repeated freeze/thaw cycles.
Stable for 1 year.
Avoid repeated freeze/thaw cycles.
Testing Data
(Image: c-KIT staining of rat skin (epidermis). c-KIT detection was done using anti-rabbit Cy3 conjugated antibodies (red color). DAPI was used to counterstain cell nuclei (blue color).Working dilution: 1:100-1:300.)
Testing Data
(Image: c-KIT staining of rat skin (epidermis). c-KIT detection was done using anti-rabbit Cy3 conjugated antibodies (red color). DAPI was used to counterstain cell nuclei (blue color).Working dilution: 1:100-1:300.)
Related Product Information for anti-c-Kit/CD117 antibody
c-Kit is transmembrane tyrosine kinase encoded by the c-Kit proto oncogene. c-Kit acts to regulate a variety of biological processes including cell proliferation, apoptosis, chemotaxis and adhesion.
It plays a critical role in activation and growth in a number of cell types such as hematopoietic stem cells, mast cells, melanocytes and germ cells.
Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.
Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.
Product Categories/Family for anti-c-Kit/CD117 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
nociceptin receptor
NCBI Official Symbol
Oprl1
NCBI Official Synonym Symbols
ORL
NCBI Protein Information
nociceptin receptor
Similar Products
Product Notes
The c-Kit/CD117 (Catalog #AAA555311) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The c-Kit, Affinity Purified Antibody, Rabbit reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's c-Kit can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC 1:100-1:400 Dilutions listed as a recommendation. Other dilutions should be determined by investigator. Researchers should empirically determine the suitability of the c-Kit/CD117 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TASSSQPLLV HDDV. It is sometimes possible for the material contained within the vial of "c-Kit, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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