Immunohistochemistry IHC
Rabbit Collagen Type VI Antibody | anti-COL6A6 antibody
Collagen Type VI antibody
Synonyms
Collagen Type VI; Collagen Type VI antibody; Polyclonal Collagen Type VI; Anti-Collagen Type VI; CollagenVI; Human mRNA for collagen VI alpha 1 C terminal globular domain; anti-COL6A6 antibody
Host
Rabbit
Form/Format
Supplied in 20mM Potassium Phosphate, pH 7.2, with 15mM Sodium Chloride, and 0.01% Sodium Azide
Concentration
1.2mg/ml by UV absorbance at 280nM (varies by lot)
Immunogen
Collagen Type VI from human and bovine placenta
Cross Reactivity
Reacts with most mammalian Type VI collagens. Less than 1% cross reactivity with Type I, II, III, IV, V collagens.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Biological Significance
Collagen is a group of naturally occurring proteins found, in nature, exclusively in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen alpha-1(VI) chain is a protein that in humans is encoded by the COL6A1 gene. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively.
Preparation and Storage
Store at 4°C as an undiluted liquid. For extended storage mix with an equal volume of gylcerol and store at -20°C or below. Avoid freeze thaw cycles.
Immunohistochemistry IHC
Immunohistochemistry IHC
Related Product Information for anti-COL6A6 antibody
Affinity purified Rabbit polyclonal Collagen Type VI antibody
Product Categories/Family for anti-COL6A6 antibody
References
Differential and restricted expression of novel collagen VI chains in mouse; Sudheer Kumar Gara, Paolo Grumati, Stefano Squarzoni, Patrizia Sabatelli, Anna Urciuolo, Paolo Bonaldo, Mats Paulsson, Raimund Wagener (Matrix Biology: Volume: 30 Issue: 4 Page: 248257 DOI: 10.1016/j.matbio.2011.03.006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
collagen alpha-6(VI) chain
NCBI Official Synonym Full Names
collagen, type VI, alpha 6
NCBI Official Symbol
COL6A6
NCBI Protein Information
collagen alpha-6(VI) chain
UniProt Protein Name
Collagen alpha-6(VI) chain
Protein Family
UniProt Gene Name
COL6A6
UniProt Entry Name
CO6A6_HUMAN
Uniprot Description
COL6A6: Collagen VI acts as a cell-binding protein. Belongs to the type VI collagen family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: proteinaceous extracellular matrix; collagen; extracellular region
Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; cell adhesion
Research Articles on COL6A6
Similar Products
Product Notes
The COL6A6 col6a6 (Catalog #AAA535250) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Collagen Type VI, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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