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Rabbit Apo CI Antibody | anti-Apo CI antibody

Rabbit Anti-Human Apo CI Antibody

Gene Names
Apoc1; Apo-CIB; ApoC-IB
Applications
ELISA
Synonyms
Apo CI; Rabbit Anti-Human Apo CI Antibody; Rabbit Anti-Human Apo CI; anti-Apo CI antibody
Ordering
For Research Use Only!
Host
Rabbit
Specificity
Specifically binds to human apo CI.
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
88
Applicable Applications for anti-Apo CI antibody
ELISA (EIA)
Application Notes
Dilution for immunoblot and ELISA range: 1:2,500 to 1:10,000
Immunogen
Apo CI recombinant protein.
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Product Categories/Family for anti-Apo CI antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,696 Da
NCBI Official Full Name
apolipoprotein C-I
NCBI Official Synonym Full Names
apolipoprotein C-I
NCBI Official Symbol
Apoc1
NCBI Official Synonym Symbols
Apo-CIB; ApoC-IB
NCBI Protein Information
apolipoprotein C-I; apo-CI; apoC-I; apolipoprotein C1
UniProt Protein Name
Apolipoprotein C-I
UniProt Gene Name
Apoc1
UniProt Synonym Gene Names
Apoc1b; Apo-CIB; ApoC-IB; Apo-CIB'; ApoC-IB'
UniProt Entry Name
APOC1_MOUSE

NCBI Description

This gene encodes a precursor plasma protein that is cleaved to yield a signal peptide and two alternatively processed mature peptides. The encoded protein, which is a component of chylomicrons, very low density lipoproteins and high density lipoproteins, transports lipids from the intestines to other locations in the body. This protein binds to free fatty acids preventing their uptake by cells. This protein is a cofactor for lecithin cholesterol acyltransferase, an enzyme that catalyzes the conversion of free cholesterol to cholesteryl esters. The encoded protein inhibits the activity of the cholesteryl ester transfer protein which promotes the exchange of neutral lipids between lipoproteins. In humans this gene is associated with risk of coronary artery disease and age-associated memory impairment. Mice lacking this gene demonstrate impaired memory. This gene is clustered with three other apolipoprotein genes on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Uniprot Description

Function: Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Ref.4

Subcellular location: Secreted.

Tissue specificity: Secreted in plasma.

Sequence similarities: Belongs to the apolipoprotein C1 family.

Research Articles on Apo CI

Similar Products

Product Notes

The Apo CI apoc1 (Catalog #AAA415402) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Apo CI can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Dilution for immunoblot and ELISA range: 1:2,500 to 1:10,000. Researchers should empirically determine the suitability of the Apo CI apoc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Apo CI, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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