Rabbit ADAM 10 (CT) Antibody | anti-ada10 antibody
Anti-ADAM10/KUZ/MADM Antibody
Applications
Immunoblot, Western Blot
Synonyms
ADAM 10 (CT); Anti-ADAM10/KUZ/MADM Antibody; Anti-ADAM 10 (CT); ADAM10/KUZ/MADM; anti-ada10 antibody
Host
Rabbit
Specificity
Anti-ADAM 10 (CT) [Rabbit antibody to peptide corresponding to aa 732-748 of human ADAM10.]
This antibody recognizes human, mouse, and rat ADAM10. A band of 85 kD is detected in immunoblots and may represent precursor. A 60 kD band is detected in some cell lines, including Jurkat and appears to be the processed mature protein.
This antibody recognizes human, mouse, and rat ADAM10. A band of 85 kD is detected in immunoblots and may represent precursor. A 60 kD band is detected in some cell lines, including Jurkat and appears to be the processed mature protein.
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma-tography.
Applicable Applications for anti-ada10 antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:2,000 dilution.
Positive control: Whole cell lysate of Jurkat cells.
Positive control: Whole cell lysate of Jurkat cells.
Antigen
Peptide corresponding to aa 732- 748 of human ADAM10. This sequence is identical to those of bovine and rat and differs from mouse by one amino acid
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-ada10 antibody
Tumor necrosis factor alpha (TNF alpha ) is a proinflammatory cytokine and contributes to a variety of inflammatory reactions and to programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including T-cell lymphoma. TNF alpha , Notch and its ligand delta are all membrane-bound molecules which are cleaved by proteases to release mature proteins or functional receptors. ADAM10, a metalloproteasedisintegrin in the famioly of mammalian ADAM (for a disintegrin and metalloprotease) was recently found to cleave TNF alpha , Notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 have been cloned and designated ADAM10, Kuzbanian (KUZ), and MADM, respectively. These genes are expressed in a variety of human and bovine tissues.
Product Categories/Family for anti-ada10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
ADAM 10
NCBI Official Symbol
ada10
NCBI Protein Information
ADAM 10
Similar Products
Product Notes
The ada10 (Catalog #AAA194018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ADAM 10 (CT) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:2,000 dilution. Positive control: Whole cell lysate of Jurkat cells. Researchers should empirically determine the suitability of the ada10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAM 10 (CT), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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