RAB3D recombinant protein
Recombinant Human RAB3D, Member RAS Oncogene Family
Gene Names
RAB3D; GOV; D2-2; RAB16; RAD3D
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
RAB3D; Recombinant Human RAB3D; Member RAS Oncogene Family; RAB3D Human; Member RAS Oncogene Family Human Recombinant; Ras-related protein Rab-3D; GOV; RAB16; D2-2; RAD3D; RAB3D recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
RAB3D protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.2M NaCl.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MASAGDTQAG PRDAADQNFD YMFKLLLIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTVYRHDKR IKLQIWDTAG QERYRTITTA YYRGAMGFLL MYDIANQESF AAVQDWATQI KTYSWDNAQV ILVGNKCDLE DERVVPAEDG RRLADDLGFE FFEASAKENI NVKQVFERLV DVICEKMNES LEPSSSSGSN GKGPAVGDAP APQPSSCSC
Sequence Length
219
Preparation and Storage
RAB3D Human Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Related Product Information for RAB3D recombinant protein
Description: RAB3D produced in E Coli is a single, non-glycosylated polypeptide chain containing 239 amino acids (1-219 a.a) and having a molecular mass of 26.4kDa (Molecular weight on SDS-PAGE will appear higher). RAB3D is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Ras-related protein Rab-3D (RAB3D) belongs to the Ras superfamily of small Rab GTPases. Rab proteins play a vital role for, either in endocytosis or in biosynthetic protein transport. Rab3D mRNA is primarily expressed in white adipose tissue and, coincident with GLUT4, increases upon differentiation of 3T3-L1 fibroblasts into insulin-responsive adipocytes. Rab3D exhibits close structural similarities with Rab 3A, an isoform which is functionally associated with regulated exocytosis in various cell types.
Introduction: Ras-related protein Rab-3D (RAB3D) belongs to the Ras superfamily of small Rab GTPases. Rab proteins play a vital role for, either in endocytosis or in biosynthetic protein transport. Rab3D mRNA is primarily expressed in white adipose tissue and, coincident with GLUT4, increases upon differentiation of 3T3-L1 fibroblasts into insulin-responsive adipocytes. Rab3D exhibits close structural similarities with Rab 3A, an isoform which is functionally associated with regulated exocytosis in various cell types.
Product Categories/Family for RAB3D recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,267 Da
NCBI Official Full Name
ras-related protein Rab-3D
NCBI Official Synonym Full Names
RAB3D, member RAS oncogene family
NCBI Official Symbol
RAB3D
NCBI Official Synonym Symbols
GOV; D2-2; RAB16; RAD3D
NCBI Protein Information
ras-related protein Rab-3D; Rab3D upregulated with myeloid differentiation; glioblastoma overexpressed
UniProt Protein Name
Ras-related protein Rab-3D
Protein Family
UniProt Gene Name
RAB3D
UniProt Synonym Gene Names
GOV; RAB16
UniProt Entry Name
RAB3D_HUMAN
Uniprot Description
RAB3D: Protein transport. Probably involved in regulated exocytosis. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: synaptic vesicle; transport vesicle; mitochondrion; secretory granule membrane; plasma membrane; endosome
Molecular Function: GTPase activity; GTPase binding; GDP binding; GTP binding; myosin V binding
Biological Process: regulation of exocytosis; intracellular protein transport; synaptic vesicle exocytosis; protein secretion; peptidyl-cysteine methylation; Rab protein signal transduction; vesicle docking during exocytosis
Research Articles on RAB3D
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Product Notes
The RAB3D rab3d (Catalog #AAA144852) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MASAGDTQAG PRDAADQNFD YMFKLLLIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTVYRHDKR IKLQIWDTAG QERYRTITTA YYRGAMGFLL MYDIANQESF AAVQDWATQI KTYSWDNAQV ILVGNKCDLE DERVVPAEDG RRLADDLGFE FFEASAKENI NVKQVFERLV DVICEKMNES LEPSSSSGSN GKGPAVGDAP APQPSSCSC< /u>. It is sometimes possible for the material contained within the vial of "RAB3D, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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