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Ihh Blocking Peptide | Q80XI9 blocking peptide

Ihh Antibody (N-term) Blocking Peptide

Gene Names
Ihh; HHG-2
Synonyms
Ihh; Ihh Antibody (N-term) Blocking Peptide; Q80XI9 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human Ihh. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
449
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Q80XI9 blocking peptide
Intercellular signal essential for a variety of patterning events during development.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
49,445 Da
NCBI Official Full Name
Indian hedgehog (Adult male intestinal mucosa cDNA, RIKEN full-length enriched library, clone:G630019N11 product:Indian hedgehog, full insert sequence)
NCBI Official Synonym Full Names
Indian hedgehog
NCBI Official Symbol
Ihh
NCBI Official Synonym Symbols
HHG-2
NCBI Protein Information
indian hedgehog protein
UniProt Protein Name
Hedgehog protein
UniProt Gene Name
Ihh
UniProt Entry Name
Q80XI9_MOUSE

Uniprot Description

IHH: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP). Expressed in embryonic lung, and in adult kidney and liver. Belongs to the hedgehog family.

Cellular Component: plasma membrane; proteinaceous extracellular matrix

Molecular Function: calcium ion binding; patched binding; protein binding

Biological Process: bone resorption; camera-type eye development; cartilage development; cell differentiation; cell fate specification; cell maturation; embryonic camera-type eye morphogenesis; embryonic development; embryonic digestive tract morphogenesis; embryonic digit morphogenesis; embryonic pattern specification; heart looping; in utero embryonic development; morphogenesis of a branching structure; multicellular organism growth; negative regulation of alpha-beta T cell differentiation; negative regulation of apoptosis; negative regulation of cell differentiation; negative regulation of eye pigmentation; negative regulation of immature T cell proliferation in the thymus; negative regulation of signal transduction; negative regulation of T cell differentiation in the thymus; neuron development; ossification; osteoblast differentiation; pancreas development; pattern specification process; patterning of blood vessels; positive regulation of alpha-beta T cell differentiation; positive regulation of cell proliferation; positive regulation of chondrocyte differentiation; positive regulation of collagen biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; positive regulation of T cell differentiation in the thymus; positive regulation of transcription from RNA polymerase II promoter; proteoglycan metabolic process; regulation of cell differentiation; regulation of growth; skeletal development; smooth muscle development; smoothened signaling pathway; vasculature development; vitelline membrane formation

Research Articles on Q80XI9

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Product Notes

The Q80XI9 ihh (Catalog #AAA9224735) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Ihh, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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