Mouse poly-U binding splicing factor 60KDa ELISA Kit | PUF60 elisa kit

Mouse Poly (U) -binding-splicing factor PUF60, PUF60 ELISA Kit

Cat. Num. AAA9329882

• Gene Names: Puf60; SIAHBP1; 2410104I19Rik; 2810454F19Rik
• Reactivity: Mouse
• Synonyms: poly-U binding splicing factor 60KDa; Mouse Poly (U) -binding-splicing factor PUF60; PUF60 ELISA Kit; Mouse Poly (U) -binding-splicing factor PUF60 (PUF60) ELISA kit; FIR; FLJ31379; RoBPI; SIAHBP1; FBP interacting repressor; Ro ribonucleoprotein binding protein 1; Ro ribonucleoprotein-binding protein 1; fuse-binding protein-interacting repressor; poly-U binding splic; PUF60 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 257196186
• NCBI GeneID: 67959
• NCBI Accession #: NP_001158072.1
• NCBI GenBank Nucleotide #: NM_001164600.1
• UniProt Accession #: Q3UEB3; Q3TGC6; Q91VR6
• Molecular Weight: 60,249 Da
• NCBI Official Full Name: poly(U)-binding-splicing factor PUF60 isoform c
• NCBI Official Synonym Full Names: poly-U binding splicing factor 60
• NCBI Official Symbol: Puf60
• NCBI Official Synonym Symbols: SIAHBP1; 2410104I19Rik; 2810454F19Rik
• NCBI Protein Information: poly(U)-binding-splicing factor PUF60; poly(U)-binding-splicing factor PUF60; 60 kDa poly(U)-binding-splicing factor; fuse-binding protein-interacting repressor
• UniProt Protein Name: Poly(U)-binding-splicing factor PUF60
• Protein Family: Poly(U)-binding-splicing factor
• UniProt Gene Name: Puf60
• UniProt Entry Name: PUF60_MOUSE

Uniprot Description

FIR: fuse-binding protein-interacting repressor. Interacts with (and may activate) Ro RNPs. Forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. Two alternatively spliced isoforms have been described.

Protein type: RNA-binding; Transcription, coactivator/corepressor; Spliceosome; RNA splicing

Cellular Component: nucleoplasm; Golgi apparatus; mitochondrion; ribonucleoprotein complex; nucleus; cyclin-dependent protein kinase activating kinase holoenzyme complex

Molecular Function: identical protein binding; DNA binding; nucleic acid binding; RNA binding; nucleotide binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis; RNA splicing; mRNA processing