Receptor-type tyrosine-protein phosphatase U (Ptpru) Recombinant Protein | Ptpru recombinant protein
Recombinant Mouse Receptor-type tyrosine-protein phosphatase U (Ptpru), partial
Gene Names
Ptpru; PTP; Pcp2; Ptpf; Ftp-1; PCP-2; Ptprl; R-PTP-U; PTPlambda; R-PTP-psi; PTP-lambda; RPTPlambda
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Receptor-type tyrosine-protein phosphatase U (Ptpru); Recombinant Mouse Receptor-type tyrosine-protein phosphatase U (Ptpru); partial; Ptpru recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
19-749
Sequence
ET ETPAAGCTFE EASDPVVPCE FSQAQYDDFQ WEQVRIHPGT RTPEDLPHGA YLMVNASQHA PGQRAHIIFQ TLSENDTHCV QFSYFLYSRD GHSPGTLGVY VRVNGGPLGS AVWNMTGSHG RQWHQAELAV STFWPNEYQV LFEALISPDH KGYIGLDDIL LFSYPCAKAP HFSRLGDVEV NAGQNASFQC MAAGRAAEAE HFFLQRQSGV LVPAAGVRHI SHRRFLATFP LASVGRSEQD LYRCVSQAPR GAGVSNFAEL IVKEPPTPIA PPQLLRAGPT YLIIQLNTNS IIGDGPIVRK EIEYRMARGP WAEVHAVNLQ TYKLWHLDPD TEYEISVLLT RPGDGGTGRP GPPLISRTKC AEPTRAPKGL AFAEIQARQL TLQWEPLGYN VTRCHTYAVS LCYRYTLGGS HNQTIRECVK MERGASRYTI KNLLPFRNIH VRLILTNPEG RKEGKEVTFQ TDEDVPGGIA AESLTFTPLE DMIFLKWEEP QEPNGLITQY EISYQSIESS DPAVNVPGPR RTISKLRNET YHVFSNLHPG TTYLFSVRAR TSKGFGQAAL TEITTNISAP SFDYADMPSP LGESENTITV LLRPAQGRGA PISVYQVVVE EERPRRLRRE PGAQDCFSVP LTFETALARG LVHYFGAELA ASSLLEAMPF TVGDNQTYRG FWNPPLEPRK AYLIYFQAAS HLKGETRLNC IRIARKAACK ESKRPLEVSQ RSEEMGLIL
Sequence Length
731
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Ptpru recombinant protein
This protein is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Three alternatively spliced transcript variants, which encode distinct proteins, have been reported.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
161,158 Da
NCBI Official Full Name
receptor-type tyrosine-protein phosphatase U isoform 2
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, U
NCBI Official Symbol
Ptpru
NCBI Official Synonym Symbols
PTP; Pcp2; Ptpf; Ftp-1; PCP-2; Ptprl; R-PTP-U; PTPlambda; R-PTP-psi; PTP-lambda; RPTPlambda
NCBI Protein Information
receptor-type tyrosine-protein phosphatase U
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase U
Protein Family
UniProt Gene Name
Ptpru
UniProt Synonym Gene Names
Pcp2; Ptpf; R-PTP-U; PCP-2; PTP-lambda; PTPlambda; R-PTP-psi
Uniprot Description
Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis ().
Research Articles on Ptpru
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Product Notes
The Ptpru ptpru (Catalog #AAA1092173) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-749. The amino acid sequence is listed below: ET ETPAAGCTFE EASDPVVPCE FSQAQYDDFQ WEQVRIHPGT RTPEDLPHGA YLMVNASQHA PGQRAHIIFQ TLSENDTHCV QFSYFLYSRD GHSPGTLGVY VRVNGGPLGS AVWNMTGSHG RQWHQAELAV STFWPNEYQV LFEALISPDH KGYIGLDDIL LFSYPCAKAP HFSRLGDVEV NAGQNASFQC MAAGRAAEAE HFFLQRQSGV LVPAAGVRHI SHRRFLATFP LASVGRSEQD LYRCVSQAPR GAGVSNFAEL IVKEPPTPIA PPQLLRAGPT YLIIQLNTNS IIGDGPIVRK EIEYRMARGP WAEVHAVNLQ TYKLWHLDPD TEYEISVLLT RPGDGGTGRP GPPLISRTKC AEPTRAPKGL AFAEIQARQL TLQWEPLGYN VTRCHTYAVS LCYRYTLGGS HNQTIRECVK MERGASRYTI KNLLPFRNIH VRLILTNPEG RKEGKEVTFQ TDEDVPGGIA AESLTFTPLE DMIFLKWEEP QEPNGLITQY EISYQSIESS DPAVNVPGPR RTISKLRNET YHVFSNLHPG TTYLFSVRAR TSKGFGQAAL TEITTNISAP SFDYADMPSP LGESENTITV LLRPAQGRGA PISVYQVVVE EERPRRLRRE PGAQDCFSVP LTFETALARG LVHYFGAELA ASSLLEAMPF TVGDNQTYRG FWNPPLEPRK AYLIYFQAAS HLKGETRLNC IRIARKAACK ESKRPLEVSQ RSEEMGLIL. It is sometimes possible for the material contained within the vial of "Receptor-type tyrosine-protein phosphatase U (Ptpru), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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