Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R) Recombinant Protein | PTH1R recombinant protein
Recombinant Didelphis marsupialis virginiana Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)
NCBI and Uniprot Product Information
Uniprot Description
Function: This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Subunit structure: Interacts (via N-terminal extracellular domain) with PTHLH and PTH. Homodimer in the absence of bound ligand. Peptide hormone binding leads to dissociation of the homodimer. Interacts (via C-terminus) with the heterodimer formed by GNG2 and GNB1
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the G-protein coupled receptor 2 family.
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Product Notes
The Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R) pth1r (Catalog #AAA1001484) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 27-585. The amino acid sequence is listed below: DADDVITKEE QIILLRNAQA QCEQRLKEVL RVPELAESAK DWMSRSAKTK KEKPAEKLYS QAEESREVSD RSRLQDGFCL PEWDNIVCWP AGVPGKVVAV PCPDYIYDFN HKGRAYRRCD SNGSWELVPG NNRTWANYSE CVKFLTNETR EREVFDRLGM IYTVGYSISL GSLTVAVLIL GYFRRLHCTR NYIHMHLFVS FMLRAVSIFI KDAVLYSGVS TDEIERITEE ELRAFTEPPP ADKAGFVGCR VAVTVFLYFL TTNYYWILVE GLYLHSLIFM AFFSEKKYLW GFTLFGWGLP AVFVAVWVTV RATLANTECW DLSSGNKKWI IQVPILAAIV VNFILFINII RVLATKLRET NAGRCDTRQQ YRKLLKSTLV LMPLFGVHYI VFMATPYTEV SGILWQVQMH YEMLFNSFQG FFVAIIYCFC NGEVQAEIKK SWSRWTLALD FKRKARSGSS TYSYGPMVSH TSVTNVGPRG GLALSLSPRL APGAGASANG HHQLPGYVKH GSISENSLPS SGPEPGTKDD GYLNGSGLYE PMVGEQPPPL LEEERETVM. It is sometimes possible for the material contained within the vial of "Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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