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Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R) Recombinant Protein | PTH1R recombinant protein

Recombinant Didelphis marsupialis virginiana Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R); Recombinant Didelphis marsupialis virginiana Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R); Recombinant Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R); Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor Parathyroid hormone 1 receptor; PTH1 receptor; PTH1R recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
27-585
Sequence
DADDVITKEEQIILLRNAQAQCEQRLKEVLRVPELAESAKDWMSRSAKTKKEKPAEKLYSQAEESREVSDRSRLQDGFCLPEWDNIVCWPAGVPGKVVAVPCPDYIYDFNHKGRAYRRCDSNGSWELVPGNNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFVSFMLRAVSIFIKDAVLYSGVSTDEIERITEEELRAFTEPPPADKAGFVGCRVAVTVFLYFLTTNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTLFGWGLPAVFVAVWVTVRATLANTECWDLSSGNKKWIIQVPILAAIVVNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGILWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSTYSYGPMVSHTSVTNVGPRGGLALSLSPRLAPGAGASANGHHQLPGYVKHGSISENSLPSSGPEPGTKDDGYLNGSGLYEPMVGEQPPPLLEEERETVM
Sequence Length
585
Species
Didelphis marsupialis virginiana (North American opossum)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
65,963 Da
NCBI Official Full Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
UniProt Protein Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
UniProt Gene Name
PTH1R
UniProt Synonym Gene Names
PTHR; PTHR1; PTH/PTHr receptor
UniProt Entry Name
PTH1R_DIDVI

Uniprot Description

Function: This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

Subunit structure: Interacts (via N-terminal extracellular domain) with PTHLH and PTH. Homodimer in the absence of bound ligand. Peptide hormone binding leads to dissociation of the homodimer. Interacts (via C-terminus) with the heterodimer formed by GNG2 and GNB1

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 2 family.

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Product Notes

The Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R) pth1r (Catalog #AAA1001484) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 27-585. The amino acid sequence is listed below: DADDVITKEE QIILLRNAQA QCEQRLKEVL RVPELAESAK DWMSRSAKTK KEKPAEKLYS QAEESREVSD RSRLQDGFCL PEWDNIVCWP AGVPGKVVAV PCPDYIYDFN HKGRAYRRCD SNGSWELVPG NNRTWANYSE CVKFLTNETR EREVFDRLGM IYTVGYSISL GSLTVAVLIL GYFRRLHCTR NYIHMHLFVS FMLRAVSIFI KDAVLYSGVS TDEIERITEE ELRAFTEPPP ADKAGFVGCR VAVTVFLYFL TTNYYWILVE GLYLHSLIFM AFFSEKKYLW GFTLFGWGLP AVFVAVWVTV RATLANTECW DLSSGNKKWI IQVPILAAIV VNFILFINII RVLATKLRET NAGRCDTRQQ YRKLLKSTLV LMPLFGVHYI VFMATPYTEV SGILWQVQMH YEMLFNSFQG FFVAIIYCFC NGEVQAEIKK SWSRWTLALD FKRKARSGSS TYSYGPMVSH TSVTNVGPRG GLALSLSPRL APGAGASANG HHQLPGYVKH GSISENSLPS SGPEPGTKDD GYLNGSGLYE PMVGEQPPPL LEEERETVM. It is sometimes possible for the material contained within the vial of "Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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