Rat Polypyrimidine tract-binding protein 1 ELISA Kit | Ptbp1 elisa kit
Rat Polypyrimidine tract-binding protein 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
DNA binding protein; involved in the negative regulation of alternative splicing [RGD, Feb 2006]
Uniprot Description
hnRNP I: a ubiquitously expressed heterogeneous nuclear ribonucleoprotein (hnRNP). hnRNPs are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. Binds to the polypyrimidine tract of introns. May promote the binding of U2 snRNP to pre-mRNA. Two alternatively spliced isoforms have been described.
Protein type: RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: 7q11
Cellular Component: cytoplasm; membrane; nucleus
Molecular Function: mRNA binding; RNA binding; sequence-specific DNA binding; single-stranded DNA binding; single-stranded DNA specific endodeoxyribonuclease activity
Biological Process: mRNA processing; negative regulation of muscle cell differentiation; negative regulation of nuclear mRNA splicing, via spliceosome; negative regulation of RNA splicing; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translation; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on Ptbp1
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Product Notes
The Rat Ptbp1 ptbp1 (Catalog #AAA9427550) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9427550 ELISA Kit recognizes Rat Ptbp1. It is sometimes possible for the material contained within the vial of "Polypyrimidine tract-binding protein 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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