Human Pregnancy-specific beta-1-glycoprotein 3 ELISA Kit | PSG3 elisa kit

Human Pregnancy-specific beta-1-glycoprotein 3 ELISA Kit

Cat. Num. AAA764680

• Reactivity: Human
• Synonyms: Pregnancy-specific beta-1-glycoprotein 3; Human Pregnancy-specific beta-1-glycoprotein 3 ELISA Kit; PSG3/PS-beta-G-3/PSBG-3/Pregnancy-specific glycoprotein 3/Pregnancy-specific beta-1-glycoprotein 3/Carcinoembryonic antigen SG5; PSG3 elisa kit

• Reactivity: Human
• Sequence Length: 428

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich ELISA, Double Antibody
• Detection Range: 15.6-1000pg/ml
• Sensitivity: 9.375pg/ml
• Preparation and Storage: Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).

Typical Testing Data

Typical Standard Curve

Related Product Information for PSG3 elisa kit

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- Human PSG3 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- Human PSG3 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and wash with wash buffer. HRPStreptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Human PSG3 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of Human PSG3 can be calculated.

NCBI and Uniprot Product Information

• NCBI GI #: 109240546
• NCBI GeneID: 5671
• NCBI Accession #: NP_066296.2
• NCBI GenBank Nucleotide #: NM_021016.3
• Molecular Weight: 47,945 Da
• NCBI Official Full Name: pregnancy-specific beta-1-glycoprotein 3
• NCBI Official Synonym Full Names: pregnancy specific beta-1-glycoprotein 3
• NCBI Official Symbol: PSG3
• NCBI Protein Information: pregnancy-specific beta-1-glycoprotein 3
• UniProt Protein Name: Pregnancy-specific beta-1-glycoprotein 3
• Protein Family: Pregnancy-specific beta-1-glycoprotein
• UniProt Gene Name: PSG3
• UniProt Synonym Gene Names: PS-beta-G-3; PSBG-3; Pregnancy-specific glycoprotein 3
• UniProt Entry Name: PSG3_HUMAN

NCBI Description

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Uniprot Description

PSG3: Belongs to the immunoglobulin superfamily. CEA family

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular region

Biological Process: defense response; female pregnancy