Myeloblastin Recombinant Protein | PRTN3 recombinant protein
Recombinant Human Myeloblastin
Gene Names
PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
Reactivity
Human
Purity
>85% (SDS-PAGE)
Synonyms
Myeloblastin; Recombinant Human Myeloblastin; AGP7C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3Neutrophil proteinase 4; NP-4P29Wegener autoantigen; PRTN3 recombinant protein
Host
E Coli
Reactivity
Human
Purity/Purification
>85% (SDS-PAGE)
Form/Format
Tris-based buffer,50% glycerol
Sequence Positions
Full Length, 28-248aa
Sequence
YMASLQMRGN PGSHFCGGTL IHPSFVLTAA HCLRDIPQRL VNVVLGAHNV RTQEPTQQHF SVAQVFLNNYDAENKLNDVL LIQLSSPANL SASVATVQLP QQDQPVPHGT QCLAMGWGRV GAHDPPAQVLQELNVTVVTF FCRPHNICTF VPRRKAGICF GDSGGP
Organism
Homo sapiens (Human)
Tag Info
N-terminal His-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stabilityof the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life oflyophilized form is 12 months at -20°C/-80°C.
Note: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Note: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Related Product Information for PRTN3 recombinant protein
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes physa when administered by tracheal insufflation to hamsters.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51.6kD
NCBI Official Full Name
myeloblastin
NCBI Official Synonym Full Names
proteinase 3
NCBI Official Symbol
PRTN3
NCBI Official Synonym Symbols
MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
NCBI Protein Information
myeloblastin
UniProt Protein Name
Myeloblastin
Protein Family
UniProt Gene Name
PRTN3
UniProt Synonym Gene Names
MBN; PR-3; PR3; NP-4
Uniprot Description
PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.
Protein type: Cell cycle regulation; EC 3.4.21.76; Protease
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytosol; extracellular matrix; extracellular region; extracellular space; plasma membrane
Molecular Function: enzyme binding; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: antimicrobial humoral response; blood coagulation; negative regulation of phagocytosis; neutrophil degranulation; positive regulation of cell proliferation
Research Articles on PRTN3
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Product Notes
The PRTN3 prtn3 (Catalog #AAA9421946) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 28-248aa. The Recombinant Human Myeloblastin reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: YMASLQMRGN PGSHFCGGTL IHPSFVLTAA HCLRDIPQRL VNVVLGAHNV RTQEPTQQHF SVAQVFLNNY DAENKLNDVL LIQLSSPANL SASVATVQLP QQDQPVPHGT QCLAMGWGRV GAHDPPAQVL QELNVTVVTF FCRPHNICTF VPRRKAGICF GDSGGP. It is sometimes possible for the material contained within the vial of "Myeloblastin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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