Western Blot (WB)
(PRTN3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRTN3 antibody detected the PRTN3 protein (arrow).)
Rabbit anti-Human PRTN3 Polyclonal Antibody | anti-PRTN3 antibody
PRTN3, CT (PRTN3, MBN, Myeloblastin, AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen) (AP)
Gene Names
PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PRTN3; Polyclonal Antibody; CT (PRTN3; MBN; Myeloblastin; AGP7; C-ANCA antigen; Leukocyte proteinase 3; Neutrophil proteinase 4; P29; Wegener autoantigen) (AP); Wegener autoantigen; anti-PRTN3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-PRTN3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PRTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the C-terminal region of human PRTN3.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(PRTN3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRTN3 antibody detected the PRTN3 protein (arrow).)
Western Blot (WB)
(PRTN3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRTN3 antibody detected the PRTN3 protein (arrow).)
Related Product Information for anti-PRTN3 antibody
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Product Categories/Family for anti-PRTN3 antibody
References
Kallquist, L., et al. Exp. Cell Res. 316(19):3182-3196(2010). Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Kuhl, A., et al. J. Immunol. 185(1):387-399(2010). Abdgawad, M., et al. Clin. Exp. Immunol. 161(1):89-97(2010). Hajjar, E., et al. FEBS J. 277(10):2238-2254(2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,807 Da
NCBI Official Full Name
myeloblastin
NCBI Official Synonym Full Names
proteinase 3
NCBI Official Symbol
PRTN3
NCBI Official Synonym Symbols
MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
NCBI Protein Information
myeloblastin; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein 7; serine proteinase, neutrophil; Wegener granulomatosis autoantigen
UniProt Protein Name
Myeloblastin
Protein Family
UniProt Gene Name
PRTN3
UniProt Synonym Gene Names
MBN; PR-3; PR3; NP-4
UniProt Entry Name
PRTN3_HUMAN
Uniprot Description
PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.
Protein type: Protease; Cell cycle regulation; EC 3.4.21.76
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: extracellular matrix; extracellular space; plasma membrane; cytosol
Molecular Function: enzyme binding; serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: negative regulation of phagocytosis; collagen catabolic process; positive regulation of cell proliferation; blood coagulation; proteolysis
Research Articles on PRTN3
Similar Products
Product Notes
The PRTN3 prtn3 (Catalog #AAA6338007) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRTN3, CT (PRTN3, MBN, Myeloblastin, AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRTN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PRTN3 prtn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRTN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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