Pre-mRNA-splicing factor 18 (Prpf18) Recombinant Protein | Prpf18 recombinant protein
Recombinant Rat Pre-mRNA-splicing factor 18 (Prpf18)
Gene Names
Prpf18; KCRF; Pprf18
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Pre-mRNA-splicing factor 18 (Prpf18); Recombinant Rat Pre-mRNA-splicing factor 18 (Prpf18); Prpf18 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-342, full length protein
Sequence
MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKVQPKEDDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPMRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNSREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
Sequence Length
342
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Prpf18 recombinant protein
Pre-mRNA splicing occurs in 2 sequential transesterification steps. This protein is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,866 Da
NCBI Official Full Name
pre-mRNA-splicing factor 18
NCBI Official Synonym Full Names
pre-mRNA processing factor 18
NCBI Official Symbol
Prpf18
NCBI Official Synonym Symbols
KCRF; Pprf18
NCBI Protein Information
pre-mRNA-splicing factor 18
UniProt Protein Name
Pre-mRNA-splicing factor 18
UniProt Gene Name
Prpf18
UniProt Synonym Gene Names
Kcrf; Prp18
NCBI Description
reduces K(+) current of G protein-activated GIRK1/4 , inward rectifier IRK1, and voltage-dependent K(V)1.1/K(V)beta1.1 K(+) channels [RGD, Feb 2006]
Uniprot Description
Participates in the second step of pre-mRNA splicing (). Down-regulates the expression of potassium channel subunits.
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Product Notes
The Prpf18 prpf18 (Catalog #AAA1455936) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-342, full length protein. The amino acid sequence is listed below: MDILKSEILR KRQLVEDRNL LVENKKYFKR SELAKKEEEA YFERCGYKVQ PKEDDQKPLT SSNPVLELEL AEEKLPMTLS RQEVIRRLRE RGEPMRLFGE TDYDAFQRLR KIEILTPEVN KGLRNDLKAA LDKIDQQYLN EIVGGQEPGE EDTQNDLKVH EENTTIEELE ALGESLGKGD DHKDMDIITK FLKFLLGVWA KELNSREDYV KRSVQGKLNS ATQKQTESYL RPLFRKLRKR NLPADIKESI TDIIKFMLQR EYVKANDAYL QMAIGNAPWP IGVTMVGIHA RTGREKIFSK HVAHVLNDET QRKYIQGLKR LMTICQKHFP TDPSKCVEYN AL. It is sometimes possible for the material contained within the vial of "Pre-mRNA-splicing factor 18 (Prpf18), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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