Testing Data
(Transferin, TF, Apotransferrin, Beta-1 Metal-binding Globulin, DKFZp781D0156, PRO1400, PRO1557, PRO2086, Serotransferrin Precursor, Siderophilin)
Transferrin, Bovine, Iron Saturated Protein | TF protein
Transferrin, Bovine, Iron Saturated (HOLO), USA Origin
Purity: 100%
Purity: 100%
fBR: Absent
BVO: Absent
Mycoplasma: Absent
BfuetonQue: Absent
Bovine Adenoviruses: Absent
Bovine Respiratory syncytial virus: Absent
Robles: Absent
Reovirus: Absent
Bovine Parvovirus: Absent
In addition, all materials were heated during processing to a temperature exceeding (65 degree C) for a period of 10 hours and subjected to a pH of 5.0 or lower for at least 3 hours. Foot and mouth disease, rinderpest, contagious bovine pleur0p.neumonia, hog cholera, swine vesticular disease and African swine fever are not known to exist in the United States. Age of bovine raw material is less than 3 year.
Testing Data
(Transferin, TF, Apotransferrin, Beta-1 Metal-binding Globulin, DKFZp781D0156, PRO1400, PRO1557, PRO2086, Serotransferrin Precursor, Siderophilin)
Testing Data
(Transferin, TF, Apotransferrin, Beta-1 Metal-binding Globulin, DKFZp781D0156, PRO1400, PRO1557, PRO2086, Serotransferrin Precursor, Siderophilin)
Isolated from fresh bovine plasma from certified USA herds and tested for adventitious viruses, bovine transferrin is an essential cellular transport protein via receptor-mediated endocytosis. Suitable for use in serum-free media and RPMI..
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
Uniprot Description
TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: extracellular space; cell surface; cytoplasmic membrane-bound vesicle; early endosome; extracellular region; coated pit; recycling endosome; perinuclear region of cytoplasm; endocytic vesicle; apical plasma membrane; late endosome; basal plasma membrane; endosome membrane; vesicle
Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding
Biological Process: platelet activation; retinal homeostasis; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport
Disease: Atransferrinemia
Research Articles on TF
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Product Notes
The TF tf (Catalog #AAA634766) is a Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Transferrin, Bovine, Iron Saturated, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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