SPRR1A protein
SPRR1a (Small Proline-Rich Repeat Protein 1A) (KLH)
Gene Names
SPRR1A; SPRK
Applications
ELISA, Western Blot
Purity
PurifiedPurified
Synonyms
SPRR1a; SPRR1a (Small Proline-Rich Repeat Protein 1A) (KLH); SPRR1A protein
Purity/Purification
Purified
Purified
Purified
Form/Format
Supplied as a liquid.
Applicable Applications for SPRR1A protein
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Immunization, Western Blot, ELISA.
Sequence (linear)
N-KLH-CPPTVTPSPYQQKTKQK-C
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for SPRR1A protein
SPRR1A belongs to a multigene family consisting of two SPRR1 genes (SPRR1A and -1B), seven SPRR2 genes (SPRR2A to -2F), and one SPRR3 gene. These genes encode small molecular weight proteins exceptionally rich in proline, cysteine and glutamate and were first identified as inducible gene products in human keratinocytes. In addition to its expression in epithelial cells, SPRR1a is localized to injured neurons and axons and is induced in neurons by axotomy where it appears to promote axonal regeneration.
Product Categories/Family for SPRR1A protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
9,877 Da
NCBI Official Full Name
SPRR1A protein
NCBI Official Synonym Full Names
small proline-rich protein 1A
NCBI Official Symbol
SPRR1A
NCBI Official Synonym Symbols
SPRK
NCBI Protein Information
cornifin-A; SPR-IA; cornifin A; 19 kDa pancornulin; small proline-rich protein IA
UniProt Protein Name
Cornifin-A
Protein Family
UniProt Gene Name
SPRR1A
UniProt Synonym Gene Names
SPR-IA
UniProt Entry Name
SPR1A_HUMAN
Uniprot Description
SPRR1A: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Belongs to the cornifin (SPRR) family.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1q21-q22
Cellular Component: cytoplasm; cornified envelope
Molecular Function: protein binding, bridging; protein binding; structural molecule activity
Biological Process: keratinocyte differentiation; epidermis development; keratinization; peptide cross-linking
Research Articles on SPRR1A
Similar Products
Product Notes
The SPRR1A sprr1a (Catalog #AAA634747) is a Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SPRR1a can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Immunization, Western Blot, ELISA. Researchers should empirically determine the suitability of the SPRR1A sprr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPRR1a, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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