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Western Blot (WB) (Western blot analysis of extracts of various cell lines using SPRR1A Polyclonal Antibody at dilution of 1:1000.)

Rabbit SPRR1A Polyclonal Antibody | anti-SPRR1A antibody

SPRR1A Polyclonal Antibody

Gene Names
SPRR1A; SPRK
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
Affinity purification
Synonyms
SPRR1A; Polyclonal Antibody; SPRR1A Polyclonal Antibody; SPRK; anti-SPRR1A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-SPRR1A antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:200
Immunogen
A synthetic peptide of Human SPRR1A
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines using SPRR1A Polyclonal Antibody at dilution of 1:1000.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines using SPRR1A Polyclonal Antibody at dilution of 1:1000.)

Immunofluorescence (IF)

(Immunofluorescence analysis of Rat skin using SPRR1A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of Rat skin using SPRR1A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF)

(Immunofluorescence analysis of Human skin using SPRR1A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of Human skin using SPRR1A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF)

(Immunofluorescence analysis of Mouse skin using SPRR1A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of Mouse skin using SPRR1A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)
Related Product Information for anti-SPRR1A antibody
SPRR1A (Small Proline Rich Protein 1A) is a Protein Coding gene. Diseases associated with SPRR1A include Progesterone-Receptor Positive Breast Cancer and Macular Degeneration, Age-Related, 13. Among its related pathways are Keratinization and Developmental Biology. Gene Ontology (GO) annotations related to this gene include structural molecule activity and protein binding, bridging. An important paralog of this gene is SPRR1B.
Product Categories/Family for anti-SPRR1A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
9,877 Da
NCBI Official Full Name
SPRR1A protein
NCBI Official Synonym Full Names
small proline-rich protein 1A
NCBI Official Symbol
SPRR1A
NCBI Official Synonym Symbols
SPRK
NCBI Protein Information
cornifin-A; SPR-IA; cornifin A; 19 kDa pancornulin; small proline-rich protein IA
UniProt Protein Name
Cornifin-A
Protein Family
UniProt Gene Name
SPRR1A
UniProt Synonym Gene Names
SPR-IA
UniProt Entry Name
SPR1A_HUMAN

Uniprot Description

SPRR1A: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Belongs to the cornifin (SPRR) family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q21-q22

Cellular Component: cytoplasm; cornified envelope

Molecular Function: protein binding, bridging; protein binding; structural molecule activity

Biological Process: keratinocyte differentiation; epidermis development; keratinization; peptide cross-linking

Research Articles on SPRR1A

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Product Notes

The SPRR1A sprr1a (Catalog #AAA2565989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPRR1A Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SPRR1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:200. Researchers should empirically determine the suitability of the SPRR1A sprr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPRR1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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