Arginine Vasopressin Receptor 1B (AVPR1B) Small Molecule | AVPR1B small molecule

OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B)

Cat. Num. AAA2086456

• Gene Names: AVPR1B; AVPR3
• Applications: SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Arginine Vasopressin Receptor 1B (AVPR1B); OVA Conjugated Arginine Vasopressin Receptor 1B (AVPR1B); AVPR1-B; AVPR3; Vasopressin 3 Receptor; Antidiuretic Hormone Receptor 1b; AVPR1B small molecule

• Host: Protein Conjugation
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 424

• Applicable Applications for AVPR1B small molecule: Immunogen, SDS-PAGE, Western Blot (WB)
• Buffer Formulation: PBS, pH7.4.
• Organism Species: Human
• Usage: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

Testing Data

Product Categories/Family for AVPR1B small molecule

Conjugated small molecules

NCBI and Uniprot Product Information

• NCBI GI #: 74418840
• NCBI GeneID: 553
• Molecular Weight: 46,971 Da
• NCBI Official Full Name: arginine vasopressin receptor 1B
• NCBI Official Synonym Full Names: arginine vasopressin receptor 1B
• NCBI Official Symbol: AVPR1B
• NCBI Official Synonym Symbols: AVPR3
• NCBI Protein Information: vasopressin V1b receptor
• UniProt Protein Name: Vasopressin V1b receptor
• Protein Family: Vasopressin V1b receptor
• UniProt Gene Name: AVPR1B
• UniProt Synonym Gene Names: AVPR3; VPR3; V1bR

NCBI Description

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]

Uniprot Description

AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: endosome; integral to plasma membrane; plasma membrane

Molecular Function: peptide binding; protein kinase C binding

Biological Process: cellular response to hormone stimulus; elevation of cytosolic calcium ion concentration; phospholipase C activation; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin