Prokineticin 2 (PK2) Recombinant Protein | PK2 recombinant protein

Recombinant Prokineticin 2 (PK2)

Cat. Num. AAA2010474

• Gene Names: Prok2; Bv8
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Prokineticin 2 (PK2); Recombinant Prokineticin 2 (PK2); PK2 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSG SEF-ITGACDK DSQCGGGMCC AVSIWVKSIR ICTPMGQVGD SCHPLTRKVP FWGRRMHHTC PCLPGLACLR TSFNRFICLA RK
• Sequence Length: 107

• Applicable Applications for PK2 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Rattus norvegicus (Rat)
• Expression System: Prokaryotic expression
• Residues: Ile29~Lys107 (Accession # Q8R413) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 20301998
• NCBI GeneID: 192206
• NCBI Accession #: NP_620207.1
• NCBI GenBank Nucleotide #: NM_138852.1
• UniProt Accession #: Q8R413
• Molecular Weight: 10.2kDa
• NCBI Official Full Name: prokineticin-2 isoform 2
• NCBI Official Synonym Full Names: prokineticin 2
• NCBI Official Symbol: Prok2
• NCBI Official Synonym Symbols: Bv8
• NCBI Protein Information: prokineticin-2; PK2; prokineticin 2 beta; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2
• UniProt Protein Name: Prokineticin-2
• Protein Family: Probable serine/threonine-protein kinase
• UniProt Gene Name: Prok2
• UniProt Synonym Gene Names: Bv8; PK2
• UniProt Entry Name: PROK2_RAT

NCBI Description

ligand of of two orphan G-protein-coupled receptors designated ZAQ and I5E [RGD, Feb 2006]

Uniprot Description

Function: May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle

By similarity.

Subcellular location: Secreted

By similarity.

Tissue specificity: Expressed at high levels in testis and at lower levels in brain, lung, ovary, spleen, thymus and uterus.

Induction: Activated by CLOCK and BMAL1 heterodimers and light; inhibited by period genes (PER1, PER2 and PER3) and cryptochrome genes (CRY1 and CRY2)

Probable.

Sequence similarities: Belongs to the AVIT (prokineticin) family.