Western Blot (WB)
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Procathepsin K Recombinant Protein
Procathepsin K protein
Purity
Procathepsin K protein was purified using a a proprietary chromatographic technique.
Synonyms
Procathepsin K; Procathepsin K protein; Procathepsin K recombinant protein
Host
Human
Purity/Purification
Procathepsin K protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in liquid form with 25 mM Tris, pH 8.0, 500 mM NaCl
Protein Type
Recombinant
Biological Significance
The protein encoded by this gene is a lysosomal cysteine protease involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is expressed predominantly in osteoclasts. Cathepsin K is a protease, which is defined by its high specificity for kinins, that is involved in bone resorption. The enzyme's ability to catabolize elastin, collagen, and gelatin allow it to break down bone and cartilage. This catabolic activity is also partially responsible for the loss of lung elasticity and recoil in emphysema. Cathepsin K inhibitors, such as odanacatib, show great potential in the treatment of osteoporosis.
Expression System
E Coli
Preparation and Storage
Store at -80 degree C
Western Blot (WB)
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Western Blot (WB)
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Related Product Information for Procathepsin K recombinant protein
Purified recombinant Human Procathepsin K protein
Product Categories/Family for Procathepsin K recombinant protein
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Product Notes
The Procathepsin K (Catalog #AAA5304291) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Procathepsin K, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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