Pollen Allergen Phl p 12 Recombinant Protein | PRO1 recombinant protein
Recombinant Pollen Allergen Phl p 12
Purity
Greater than 80.0% as determined by SDS-PAGE.
Synonyms
Pollen Allergen Phl p 12; Recombinant Pollen Allergen Phl p 12; Pollen Allergen Phl p 12 Recombinant; Profilin-1; Allergen Phl p 11; Pollen allergen Phl p 12; Phl p 12; PRO1; PHLPXI; PRO1 recombinant protein
Host
Sf9 insect cells.
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Form/Format
Sterile filtered clear solution.
Supplied in 20mM HEPES buffer pH-7.5, 250mM NaCl and 20% glycerol.
Supplied in 20mM HEPES buffer pH-7.5, 250mM NaCl and 20% glycerol.
Sequence Length
131
Immunological Functions
1. Binds IgE type human antibodies.
2. Immunodot test with positive/negative sera panels.
2. Immunodot test with positive/negative sera panels.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.
Avoid multiple freeze-thaw cycles.
Avoid multiple freeze-thaw cycles.
Related Product Information for PRO1 recombinant protein
Description: Recombinant PhI p 12 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 15,607 Dalton. PhI p 12 is expressed with a 10xHis tag at N-terminus and purified by proprietary chromatographic techniques.
Introductions: Phl p 12.0101 a profilin, is a minor grass pollen allergen which is involved in cytoskeleton mobility by interacting with actin filaments. It is well recognized that IgE binding can cause immune cross-reactivity with profilins of plant-derived foods and pollen profilin.
Introductions: Phl p 12.0101 a profilin, is a minor grass pollen allergen which is involved in cytoskeleton mobility by interacting with actin filaments. It is well recognized that IgE binding can cause immune cross-reactivity with profilins of plant-derived foods and pollen profilin.
Product Categories/Family for PRO1 recombinant protein
NCBI and Uniprot Product Information
Uniprot Description
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.MiscellaneousThe variability of the residues taking part of IgE-binding epitopes might be responsible of the difference in cross-reactivity among olive pollen cultivars, and between distantly related pollen species, leading to a variable range of allergy reactions among atopic patients.
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Product Notes
The Pollen Allergen Phl p 12 pro1 (Catalog #AAA141200) is a Recombinant Protein produced from Sf9 insect cells. and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Pollen Allergen Phl p 12, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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