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Protein arginine N-methyltransferase 8 (PRMT8) Recombinant Protein | PRMT8 recombinant protein

Recombinant Human Protein arginine N-methyltransferase 8 (PRMT8)

Gene Names
PRMT8; HRMT1L3; HRMT1L4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protein arginine N-methyltransferase 8 (PRMT8); Recombinant Human Protein arginine N-methyltransferase 8 (PRMT8); PRMT8 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-394, Full length protein
Sequence
GMKHSSRCLLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR
Sequence Length
393
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,169 Da
NCBI Official Full Name
protein arginine N-methyltransferase 8 isoform 2
NCBI Official Synonym Full Names
protein arginine methyltransferase 8
NCBI Official Symbol
PRMT8
NCBI Official Synonym Symbols
HRMT1L3; HRMT1L4
NCBI Protein Information
protein arginine N-methyltransferase 8
UniProt Protein Name
Protein arginine N-methyltransferase 8
UniProt Gene Name
PRMT8
UniProt Synonym Gene Names
HRMT1L3; HRMT1L4

NCBI Description

Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]

Uniprot Description

Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.

Research Articles on PRMT8

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Product Notes

The PRMT8 prmt8 (Catalog #AAA1380505) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-394, Full length protein. The amino acid sequence is listed below: GMKHSSRCLL LRRKMAENAA ESTEVNSPPS QPPQPVVPAK PVQCVHHVST QPSCPGRGKM SKLLNPEEMT SRDYYFDSYA HFGIHEEMLK DEVRTLTYRN SMYHNKHVFK DKVVLDVGSG TGILSMFAAK AGAKKVFGIE CSSISDYSEK IIKANHLDNI ITIFKGKVEE VELPVEKVDI IISEWMGYCL FYESMLNTVI FARDKWLKPG GLMFPDRAAL YVVAIEDRQY KDFKIHWWEN VYGFDMTCIR DVAMKEPLVD IVDPKQVVTN ACLIKEVDIY TVKTEELSFT SAFCLQIQRN DYVHALVTYF NIEFTKCHKK MGFSTAPDAP YTHWKQTVFY LEDYLTVRRG EEIYGTISMK PNAKNVRDLD FTVDLDFKGQ LCETSVSNDY KMR. It is sometimes possible for the material contained within the vial of "Protein arginine N-methyltransferase 8 (PRMT8), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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