Western Blot (WB)
(Western blot analysis of lysates from human brain, mouse brain tissue lysate (from left to right), using PRMT8 Antibody (C-term). MBS9205683 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Rabbit PRMT8 Polyclonal Antibody | anti-PRMT8 antibody
PRMT8 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from human brain, mouse brain tissue lysate (from left to right), using PRMT8 Antibody (C-term). MBS9205683 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from human brain, mouse brain tissue lysate (from left to right), using PRMT8 Antibody (C-term). MBS9205683 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of PRMT8 Antibody (C-term) in K562 cell line lysates (35ug/lane). PRMT8 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of PRMT8 Antibody (C-term) in K562 cell line lysates (35ug/lane). PRMT8 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of PRMT8 (arrow) using rabbit polyclonal PRMT8 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2) (Origene Technologies).)
Western Blot (WB)
(Western blot analysis of PRMT8 (arrow) using rabbit polyclonal PRMT8 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2) (Origene Technologies).)
NCBI and Uniprot Product Information
NCBI Description
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
Uniprot Description
PRMT8: Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS. Belongs to the protein arginine N-methyltransferase family. PRMT8 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Methyltransferase; EC 2.1.1.-; Methyltransferase, protein arginine
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: plasma membrane; cytosol; nucleus
Molecular Function: protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity; S-adenosylmethionine-dependent methyltransferase activity; histone-arginine N-methyltransferase activity
Biological Process: histone methylation; peptidyl-arginine methylation; regulation of transcription, DNA-dependent; regulation of protein binding; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
Research Articles on PRMT8
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Product Notes
The PRMT8 prmt8 (Catalog #AAA9205683) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 344-373. The PRMT8 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's PRMT8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PRMT8 prmt8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRMT8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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