PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A Recombinant Protein | PPP1R1A recombinant protein
Human PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A Recombinant Protein
Gene Names
PPP1R1A; I1; IPP1
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A; Human PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A Recombinant Protein; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1; I-1; IPP1; PPP1R1A recombinant protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
171
Applicable Applications for PPP1R1A recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Interacts with PPP1R15A.
Entry Function
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 1A
NCBI Official Synonym Full Names
protein phosphatase 1 regulatory inhibitor subunit 1A
NCBI Official Symbol
PPP1R1A
NCBI Official Synonym Symbols
I1; IPP1
NCBI Protein Information
protein phosphatase 1 regulatory subunit 1A
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 1A
Protein Family
UniProt Gene Name
PPP1R1A
UniProt Synonym Gene Names
IPP1; I-1; IPP-1
UniProt Entry Name
PPR1A_HUMAN
Uniprot Description
PPP1R1A: protein phosphatase 1, regulatory (inhibitor) subunit 1A. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Protein type: Protein phosphatase, regulatory subunit; Inhibitor
Chromosomal Location of Human Ortholog: 12q13.2
Cellular Component: extracellular space; cytoplasm
Molecular Function: protein binding; type 1 serine/threonine specific protein phosphatase inhibitor activity
Biological Process: glycogen metabolic process; negative regulation of protein kinase activity
Research Articles on PPP1R1A
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Product Notes
The PPP1R1A ppp1r1a (Catalog #AAA2902927) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the PPP1R1A ppp1r1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP1R1A / Protein Phosphatase 1 Regulatory Subunit 1A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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