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Peptidyl-Prolyl Cis-Trans Isomerase H/PPIH Recombinant Protein | PPIH recombinant protein

Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase H/PPIH Protein (N-6His)

Gene Names
PPIH; CYPH; CYP-20; USA-CYP; SnuCyp-20
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Peptidyl-Prolyl Cis-Trans Isomerase H/PPIH; Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase H/PPIH Protein (N-6His); Peptidyl-Prolyl Cis-Trans Isomerase H; PPIase H; Rotamase H; Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H; CypH; U-snRNP-Associated Cyclophilin SnuCyp-20; USA-CYP; PPIH; CYP20; CYPH; PPIH recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Sequence Positions
Met1-Met177
Sequence Length
134
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
N-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for PPIH recombinant protein
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 21.4 kDa
Actual Protein Molecular Mass: 18 kDa
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase H isoform 2
NCBI Official Synonym Full Names
peptidylprolyl isomerase H
NCBI Official Symbol
PPIH
NCBI Official Synonym Symbols
CYPH; CYP-20; USA-CYP; SnuCyp-20
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase H
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase H
UniProt Gene Name
PPIH
UniProt Synonym Gene Names
CYP20; CYPH; PPIase H; CypH; USA-CYP

NCBI Description

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]

Uniprot Description

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone.

Research Articles on PPIH

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Product Notes

The PPIH ppih (Catalog #AAA2553074) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Met177. It is sometimes possible for the material contained within the vial of "Peptidyl-Prolyl Cis-Trans Isomerase H/PPIH, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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