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Pyrophosphatase-2 Recombinant Protein | PPA2 recombinant protein

Recombinant Human Pyrophosphatase-2

Gene Names
PPA2; HSPC124; SID6-306
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Pyrophosphatase-2; Recombinant Human Pyrophosphatase-2; PPA2 Human; Pyrophosphatase-2 Human Recombinant; PPA2; Inorganic pyrophosphatase 2; mitochondrial; PPase 2; Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; HSPC124; Pyrophosphatase (inorganic) 2; SID6-306; mitochondrial isoform 1; PPA2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
PPA2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol, 1mM DTT.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSALYHTEE RGQPCSQNYR LFFKNVTGHY ISPFHDIPLK VNSKEENGIP MKKARNDEYE NLFNMIVEIP RWTNAKMEIA TKEPMNPIKQ YVKDGKLRYV ANIFPYKGYI WNYGTLPQTW EDPHEKDKST NCFGDNDPID VCEIGSKILS CGEVIHVKIL GILALIDEGE TDWKLIAINA NDPEASKFHD IDDVKKFKPG YLEATLNWFR LYKVPDGKPE NQFAFNGEFK NKAFALEVIK STHQCWKALL MKKCNGGAIN CTNVQISDSP FRCTQEEARS LVESVSSSPN KESNEEEQVW HFLGK.
Sequence Length
305
Related Product Information for PPA2 recombinant protein
Introduction: PPA2 shares great imagination with members of the inorganic pyrophosphatase (PPase) family. PPA2 is localized to the mitochondrion and owns the signature sequence necessary for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is vital for the phosphate metabolism of cells.

Description: PPA2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 325 amino acids (33-334 a.a) and having a molecular mass of 37.1kDa.PPA2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for PPA2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,992 Da
NCBI Official Full Name
inorganic pyrophosphatase 2, mitochondrial isoform 2
NCBI Official Synonym Full Names
pyrophosphatase (inorganic) 2
NCBI Official Symbol
PPA2
NCBI Official Synonym Symbols
HSPC124; SID6-306
NCBI Protein Information
inorganic pyrophosphatase 2, mitochondrial
UniProt Protein Name
Inorganic pyrophosphatase 2, mitochondrial
UniProt Gene Name
PPA2
UniProt Synonym Gene Names
PPase 2
UniProt Entry Name
IPYR2_HUMAN

Uniprot Description

PPA2: is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Protein type: EC 3.6.1.1; Energy Metabolism - oxidative phosphorylation; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: mitochondrial matrix

Molecular Function: inorganic diphosphatase activity

Biological Process: tRNA aminoacylation for protein translation

Disease: Sudden Cardiac Failure, Alcohol-induced; Sudden Cardiac Failure, Infantile

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Product Notes

The PPA2 ppa2 (Catalog #AAA140673) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSALY HTEE RGQPCSQNYR LFFKNVTGHY ISPFHDIPLK VNSKEENGIP MKKARNDEYE NLFNMIVEIP RWTNAKMEIA TKEPMNPIKQ YVKDGKLRYV ANIFPYKGYI WNYGTLPQTW EDPHEKDKST NCFGDNDPID VCEIGSKILS CGEVIHVKIL GILALIDEGE TDWKLIAINA NDPEASKFHD IDDVKKFKPG YLEATLNWFR LYKVPDGKPE NQFAFNGEFK NKAFALEVIK STHQCWKALL MKKCNGGAIN CTNVQISDSP FRCTQEEARS LVESVSSSPN KESNEEEQVW HFLGK.. It is sometimes possible for the material contained within the vial of "Pyrophosphatase-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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