Glyceraldehyde 3-Phosphate Dehydrogenase Peptide Enzyme

Glyceraldehyde 3-Phosphate Dehydrogenase Peptide (79-86) (porcine) (GAPD, GAPDH)

Cat. Num. AAA653927

• Reactivity: Porcine
• Purity: Highly Purified; Purified by HPLC (~95%).
• Synonyms: Glyceraldehyde 3-Phosphate Dehydrogenase Peptide; Glyceraldehyde 3-Phosphate Dehydrogenase Peptide (79-86) (porcine) (GAPD; GAPDH); Glyceraldehyde 3-Phosphate Dehydrogenase Peptide enzyme

• Host: Porcine, synthetic peptide
• Reactivity: Porcine
• Purity/Purification: Highly Purified; Purified by HPLC (~95%).
• Form/Format: Supplied as a lyophilized powder.

• Sequence (linear): Pro-Ala-Asn-Ile-Lys-Trp-Gly-Asp; Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. Besides functioning as a glycolytic enzyme in cytoplasm, evidence suggests that mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication and DNA repair. During the last decade, many findings have been made concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death and age-related neuronal diseases such as Alzheimer's and Huntington's. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kD subunits. The molecular weight for GAPDH is 146kD.
• Preparation and Storage: Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for Glyceraldehyde 3-Phosphate Dehydrogenase Peptide enzyme

Molecular Biology; MB-Enzymes; Dehydrogenase

NCBI and Uniprot Product Information

• NCBI GI #: 999157
• NCBI Official Full Name: glyceraldehyde-3-phosphate dehydrogenase, NAPDH, p36 {internal fragment}