Porcine Tyrosine Kinase 2 (Tyk-2) ELISA Kit | Tyk-2 elisa kit

Porcine Tyrosine Kinase 2 (Tyk-2) ELISA Kit

Gene Names

TYK2; JTK1; IMD35

Reactivity

Porcine

Synonyms

Tyrosine Kinase 2 (Tyk-2); Porcine Tyrosine Kinase 2 (Tyk-2) ELISA Kit; Tyk-2 elisa kit

Ordering
Cat. Num. AAA268392 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Porcine

Sequence Length

1187

Preparation and Storage

Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

NCBI GI #

15559784

NCBI GeneID

7297

Molecular Weight

133,650 Da

NCBI Official Full Name

Tyrosine kinase 2

NCBI Official Synonym Full Names

tyrosine kinase 2

NCBI Official Symbol

TYK2

NCBI Official Synonym Symbols

JTK1; IMD35

NCBI Protein Information

non-receptor tyrosine-protein kinase TYK2

UniProt Protein Name

Non-receptor tyrosine-protein kinase TYK2

UniProt Gene Name

TYK2

UniProt Entry Name

TYK2_HUMAN

NCBI Description

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

Uniprot Description

Tyk2: a non-receptor tyrosine-protein kinase of the JakA family. Activated in signaling from the IL-2, gp130 and IFN families of receptors. Phosphorylates the interferon-alpha/beta receptor alpha chain.

Protein type: Kinase, protein; EC 2.7.10.2; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group; JakA family

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; cytoplasm; cytosol; nucleus

Molecular Function: protein binding; growth hormone receptor binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; type 1 angiotensin receptor binding; ATP binding

Biological Process: cell migration; cytokine and chemokine mediated signaling pathway; innate immune response; cell differentiation; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation

Disease: Immunodeficiency 35

Research Articles on Tyk-2

1. Here, we report the 2.8-A structure of the two-domain pseudokinase-kinase module from the JAK family member TYK2 in its autoinhibited form.

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Product Notes

The Porcine Tyk-2 tyk2 (Catalog #AAA268392) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA268392 ELISA Kit recognizes Porcine Tyk-2. It is sometimes possible for the material contained within the vial of "Tyrosine Kinase 2 (Tyk-2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Porcine Tyrosine Kinase 2 (Tyk-2) ELISA Kit | Tyk-2 elisa kit