Porcine Pachytene checkpoint protein 2 homolog (TRIP13) ELISA Kit | TRIP13 elisa kit
Porcine Pachytene checkpoint protein 2 homolog (TRIP13) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009]
Uniprot Description
TRIP13: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Belongs to the AAA ATPase family. PCH2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 5p15.33
Cellular Component: male germ cell nucleus; nucleus
Molecular Function: identical protein binding; protein binding; transcription cofactor activity; ATP binding
Biological Process: oogenesis; transcription from RNA polymerase II promoter; synaptonemal complex assembly; male meiosis I; meiotic recombination; double-strand break repair; spermatogenesis; oocyte maturation; spermatid development; female meiosis I
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Product Notes
The Porcine TRIP13 trip13 (Catalog #AAA7224820) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7224820 ELISA Kit recognizes Porcine TRIP13. It is sometimes possible for the material contained within the vial of "Pachytene checkpoint protein 2 homolog (TRIP13), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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