Porcine cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA) ELISA Kit | PRKACA elisa kit
Porcine cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
active catalytic subunit of protein kinase A; phosphorylates and activates transcription factors in response to elevated levels of cAMP; mediates phosphorylation and regulation of enzyme substrates involved in intermediary metabolism [RGD, Feb 2006]
Uniprot Description
PKACA: catalytic subunit of cAMP-dependent protein kinase alpha, an AGC kinase. A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Two splice-variant isoforms have been described.
Protein type: Kinase, protein; Protein kinase, AGC; EC 2.7.11.11; Protein kinase, Ser/Thr (non-receptor); AGC group; PKA family
Cellular Component: AMP-activated protein kinase complex; cAMP-dependent protein kinase complex; centrosome; cytoplasm; cytosol; Golgi apparatus; membrane; mitochondrion; neuromuscular junction; neuron projection; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; protein complex
Molecular Function: ATP binding; cAMP-dependent protein kinase activity; protein binding; protein complex binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; Rab GTPase binding; ubiquitin protein ligase binding
Biological Process: mesoderm formation; negative regulation of meiotic cell cycle; neural tube closure; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of cell proliferation; positive regulation of protein export from nucleus; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of cellular respiration; regulation of osteoblast differentiation; regulation of synaptic transmission; regulation of synaptic transmission, glutamatergic; sperm capacitation
Research Articles on PRKACA
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Product Notes
The Porcine PRKACA prkaca (Catalog #AAA9365600) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9365600 ELISA Kit recognizes Porcine PRKACA. It is sometimes possible for the material contained within the vial of "cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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