Porcine ATP synthase subunit d, mitochondrial (ATP5H) ELISA Kit | ATP5H elisa kit

Porcine ATP synthase subunit d, mitochondrial (ATP5H) ELISA Kit

Cat. Num. AAA7209564

• Gene Names: ATP5H; ATPQ
• Reactivity: Porcine
• Synonyms: ATP synthase subunit d; mitochondrial (ATP5H); Porcine ATP synthase subunit d; mitochondrial (ATP5H) ELISA Kit; ATP5H elisa kit

• Reactivity: Porcine

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for ATP5H elisa kit

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 51479152
• NCBI GeneID: 10476
• NCBI Accession #: NP_001003785.1
• NCBI GenBank Nucleotide #: NM_001003785.1
• Molecular Weight: 15,773 Da
• NCBI Official Full Name: ATP synthase subunit d, mitochondrial isoform b
• NCBI Official Synonym Full Names: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
• NCBI Official Symbol: ATP5H
• NCBI Official Synonym Symbols: ATPQ
• NCBI Protein Information: ATP synthase subunit d, mitochondrial; My032 protein; ATPase subunit d; ATP synthase D chain, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1F0, subunit d; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d
• UniProt Protein Name: ATP synthase subunit d, mitochondrial
• UniProt Gene Name: ATP5H
• UniProt Synonym Gene Names: My032; ATPase subunit d
• UniProt Entry Name: ATP5H_HUMAN

NCBI Description

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15. [provided by RefSeq, Jun 2010]

Uniprot Description

ATP5H: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Belongs to the ATPase d subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Mitochondrial

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: nucleoplasm; mitochondrion; cytoplasm; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex

Molecular Function: ATPase activity; transmembrane transporter activity; hydrogen ion transmembrane transporter activity

Biological Process: cellular metabolic process; mitochondrial ATP synthesis coupled proton transport