Porcine ATP-sensitive inward rectifier potassium channel 12 (KCNJ12) ELISA Kit | KCNJ12 elisa kit
Porcine ATP-sensitive inward rectifier potassium channel 12 (KCNJ12) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Uniprot Description
KCNJ12: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: integral to plasma membrane; plasma membrane; intrinsic to membrane
Molecular Function: inward rectifier potassium channel activity
Biological Process: synaptic transmission; muscle contraction; potassium ion import; potassium ion transport; regulation of heart contraction; protein homotetramerization
Research Articles on KCNJ12
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Product Notes
The Porcine KCNJ12 kcnj12 (Catalog #AAA7226672) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7226672 ELISA Kit recognizes Porcine KCNJ12. It is sometimes possible for the material contained within the vial of "ATP-sensitive inward rectifier potassium channel 12 (KCNJ12), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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