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Western Blot (WB) (Western blot analysis of A172 Hela Hepg2 and K562 cell lysates using ZUFSP Polyclonal Antibody at dilution of 1:300)

Rabbit ZUFSP Polyclonal Antibody | anti-ZUFSP antibody

ZUFSP Polyclonal Antibody

Gene Names
ZUP1; DUB; ZUFSP; C6orf113
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Antigen affinity purification
Synonyms
ZUFSP; Polyclonal Antibody; ZUFSP Polyclonal Antibody; C6orf113; Chromosome 6 open reading frame 113; DJ412I7.3; RP3-412I7.3; Zinc finger with UFM1 specific peptidase domain; Zinc finger with UFM1 specific peptidase domain protein; Zinc finger with UFM1-specific peptidase domain protein; Zufsp; anti-ZUFSP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Applicable Applications for anti-ZUFSP antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:25-1:100
ELISA: 1:5000-1:10000
Note: Centrifuge before opening to ensure complete recovery of vial contents.
Note
Centrifuge before opening to ensure complete recovery of vial contents
Immunogen
Fusion protein of human ZUFSP
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of A172 Hela Hepg2 and K562 cell lysates using ZUFSP Polyclonal Antibody at dilution of 1:300)

Western Blot (WB) (Western blot analysis of A172 Hela Hepg2 and K562 cell lysates using ZUFSP Polyclonal Antibody at dilution of 1:300)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZUFSP Polyclonal Antibody at dilution of 1:35(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZUFSP Polyclonal Antibody at dilution of 1:35(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZUFSP Polyclonal Antibody at dilution of 1:35(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZUFSP Polyclonal Antibody at dilution of 1:35(×200))
Related Product Information for anti-ZUFSP antibody
Making up nearly 6% of the human genome, chromosome 6 contains around 1, 200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.
Product Categories/Family for anti-ZUFSP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66 kDa
NCBI Official Full Name
zinc finger-containing ubiquitin peptidase 1 isoform 1
NCBI Official Synonym Full Names
zinc finger containing ubiquitin peptidase 1
NCBI Official Symbol
ZUP1
NCBI Official Synonym Symbols
DUB; ZUFSP; C6orf113
NCBI Protein Information
zinc finger-containing ubiquitin peptidase 1
UniProt Protein Name
Zinc finger with UFM1-specific peptidase domain protein
UniProt Gene Name
ZUFSP
UniProt Synonym Gene Names
C6orf113
UniProt Entry Name
ZUFSP_HUMAN

NCBI Description

This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018]

Research Articles on ZUFSP

Similar Products

Product Notes

The ZUFSP zufsp (Catalog #AAA2560365) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZUFSP Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZUFSP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:25-1:100 ELISA: 1:5000-1:10000 Note: Centrifuge before opening to ensure complete recovery of vial contents. Researchers should empirically determine the suitability of the ZUFSP zufsp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZUFSP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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