Rabbit anti-Human ZNF674 Polyclonal Antibody | anti-ZNF674 antibody

ZNF674, NT (ZNF674, Zinc finger protein 674)

Cat. Num. AAA6000830

• Gene Names: ZNF674; MRX92; ZNF673B
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ZNF674; Polyclonal Antibody; NT (ZNF674; Zinc finger protein 674); Anti -ZNF674; anti-ZNF674 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-ZNF674 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: ZNF674 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human ZNF674.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ZNF674 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ZNF674 antibody detected the ZNF674 protein (arrow).)

Related Product Information for anti-ZNF674 antibody

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Product Categories/Family for anti-ZNF674 antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 298676524
• NCBI GeneID: 641339
• NCBI Accession #: NP_001177346.1
• NCBI GenBank Nucleotide #: NM_001190417.1
• UniProt Accession #: Q2M3X9; B4DHE2; E9PHQ4
• Molecular Weight: 67,199 Da
• NCBI Official Full Name: zinc finger protein 674 isoform 3
• NCBI Official Synonym Full Names: zinc finger protein 674
• NCBI Official Symbol: ZNF674
• NCBI Official Synonym Symbols: MRX92; ZNF673B
• NCBI Protein Information: zinc finger protein 674; zinc finger family member 674
• UniProt Protein Name: Zinc finger protein 674
• Protein Family: Zinc finger protein
• UniProt Gene Name: ZNF674
• UniProt Entry Name: ZN674_HUMAN

NCBI Description

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

Uniprot Description

ZNF674: May be involved in transcriptional regulation. Defects in ZNF674 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: Xp11.3

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent