Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20,)
Rabbit anti-Human ZNF268 Polyclonal Antibody | anti-ZNF268 antibody
ZNF268 Antibody
Gene Names
ZNF268; HZF3
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
ZNF268; Polyclonal Antibody; ZNF268 Antibody; HZF3; anti-ZNF268 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total ZNF268 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.9 mg/ml (varies by lot)
Sequence Length
947
Applicable Applications for anti-ZNF268 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen
Fusion protein of human ZNF268
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20,)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20,)
Related Product Information for anti-ZNF268 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoformsof ZNF268 exist as a result of alternative splicing events.
Product Categories/Family for anti-ZNF268 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,931 Da
NCBI Official Full Name
zinc finger protein 268 isoform a
NCBI Official Synonym Full Names
zinc finger protein 268
NCBI Official Symbol
ZNF268
NCBI Official Synonym Symbols
HZF3
NCBI Protein Information
zinc finger protein 268
UniProt Protein Name
Zinc finger protein 268
Protein Family
UniProt Gene Name
ZNF268
UniProt Entry Name
ZN268_HUMAN
Uniprot Description
ZNF268: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; DNA-binding
Chromosomal Location of Human Ortholog: 12q24.33
Cellular Component: actin cytoskeleton; cytoplasm; nucleus
Molecular Function: transcription factor activity
Biological Process: negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of apoptosis; positive regulation of cell differentiation; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter, mitotic; regulation of mitotic cell cycle
Similar Products
Product Notes
The ZNF268 znf268 (Catalog #AAA9415293) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF268 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF268 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the ZNF268 znf268 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF268, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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