Rabbit anti-Human, Mouse ZNF259 Polyclonal Antibody | anti-ZNF259 antibody

ZNF259, CT (ZNF259, ZPR1, Zinc finger protein ZPR1, Zinc finger protein 259) (Azide free) (HRP)

Cat. Num. AAA6366023

• Gene Names: ZNF259; ZPR1
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ZNF259; Polyclonal Antibody; CT (ZNF259; ZPR1; Zinc finger protein ZPR1; Zinc finger protein 259) (Azide free) (HRP); Zinc finger protein 259; anti-ZNF259 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-ZNF259 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ZNF259 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-434 amino acids from the C-terminal region of human ZNF259.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ZNF259 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ZNF259 antibody detected the ZNF259 protein (arrow).)

Western Blot (WB)

(ZNF259 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the ZNF259 antibody detected the ZNF259 protein (arrow).)

Related Product Information for anti-ZNF259 antibody

ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus.

Product Categories/Family for anti-ZNF259 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010). Suchindran, S., et al. PLoS Genet. 6 (4), E1000928 (2010): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 4508021
• NCBI GeneID: 8882
• NCBI Accession #: NP_003895.1
• NCBI GenBank Nucleotide #: NM_003904.3
• UniProt Accession #: O75312; Q2TAA0
• Molecular Weight: 50,925 Da
• NCBI Official Full Name: zinc finger protein ZPR1
• NCBI Official Synonym Full Names: zinc finger protein 259
• NCBI Official Symbol: ZNF259
• NCBI Official Synonym Symbols: ZPR1
• NCBI Protein Information: zinc finger protein ZPR1
• UniProt Protein Name: Zinc finger protein ZPR1
• UniProt Gene Name: ZPR1
• UniProt Synonym Gene Names: ZNF259
• UniProt Entry Name: ZPR1_HUMAN

Uniprot Description

ZNF259: May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. Binds to the EGF and PDGF receptors. Binds to the elongation factor 1-alpha EF1A. Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Belongs to the ZPR1 family.

Protein type: Nucleolus; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: nucleoplasm; Cajal body; growth cone; cell soma; perinuclear region of cytoplasm; axon; cytoplasm; nucleolus; perikaryon; SMN complex; nucleus

Molecular Function: protein binding; zinc ion binding; translation initiation factor binding; receptor tyrosine kinase binding

Biological Process: cell proliferation; regulation of myelination; trophectodermal cell proliferation; positive regulation of protein import into nucleus; spinal cord development; RNA splicing; DNA endoreduplication; Cajal body organization and biogenesis; microtubule cytoskeleton organization and biogenesis; mRNA processing; signal transduction; positive regulation of RNA splicing; positive regulation of growth; inner cell mass cell proliferation