Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using ZMYND8 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.)
Rabbit ZMYND8 Polyclonal Antibody | anti-ZMYND8 antibody
ZMYND8 Polyclonal Antibody
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using ZMYND8 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using ZMYND8 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.)
NCBI and Uniprot Product Information
Molecular Weight: 1186
NCBI Description
The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
RACK7: a DNA damage response (DDR) protein, receptor for activated C-kinase (RACK) protein, and a transcriptional regulator. A bromodomain (BRD)-containing protein that recruits the nucleosome remodeling and histone deacetylation (NuRD) complex to damaged chromatin. Targets DNA damage within actively transcribed regions, repressing transcription, and promoting repair by homologous recombination. A cutaneous T-cell lymphoma-associated antigen that contains a bromodomain and two zinc fingers. Twenty-two alternatively spliced isoforms of the human protein hve been reported.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 20q13.12
Cellular Component: cytoplasm; dendritic shaft; dendritic spine; nucleus
Molecular Function: chromatin binding; histone binding; protein binding; protein N-terminus binding; transcription cofactor activity; zinc ion binding
Biological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of filopodium formation; regulation of transcription, DNA-dependent
Research Articles on ZMYND8
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Product Notes
The ZMYND8 zmynd8 (Catalog #AAA9129511) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMYND8 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZMYND8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB: 1:500 - 1:2000, IHC: 1:20 - 1:200, IP: 1:20 - 1:50. Researchers should empirically determine the suitability of the ZMYND8 zmynd8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZMYND8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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