Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of Zic1/2/3 (D348) pAb in paraffin-embedded human brain tissue.)
Rabbit Zic1/2/3 Polyclonal Antibody | anti-Zic1/2/3 antibody
Zic1/2/3 (D348) Polyclonal Antibody
Gene Names
ZIC1; ZIC; CRS6; BAIDCS; ZNF201
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
Zic1/2/3; Polyclonal Antibody; Zic1/2/3 (D348) Polyclonal Antibody; Zinc finger protein ZIC 1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; ZIC1; ZIC; ZNF201; Zinc finger protein ZIC 2; Zinc finger protein of the cerebellum 2; ZIC2; Zinc finger protein ZIC 3; Zinc finger protein 203; Zinc finger protein of the cerebellum 3; ZIC3; ZNF203; anti-Zic1/2/3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Zic1/2/3 (D348) polyclonal antibody detects endogenous levels of Zic1/2/3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
447
Applicable Applications for anti-Zic1/2/3 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:50-1:200
IF: 1:50-1:200
IF: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to amino acids 318-366 of Human Zic1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of Zic1/2/3 (D348) pAb in paraffin-embedded human brain tissue.)
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of Zic1/2/3 (D348) pAb in paraffin-embedded human brain tissue.)
Related Product Information for anti-Zic1/2/3 antibody
Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation, becoming restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. The Zic1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic1 gene contains a region-specific enhancer determined to be essential in in-vivo and in-vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family. Zic2 and Zic3 are highly similar genes. Zic2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~ 51kDa
NCBI Official Full Name
zinc finger protein ZIC 1
NCBI Official Synonym Full Names
Zic family member 1
NCBI Official Symbol
ZIC1
NCBI Official Synonym Symbols
ZIC; CRS6; BAIDCS; ZNF201
NCBI Protein Information
zinc finger protein ZIC 1
UniProt Protein Name
Zinc finger protein ZIC 1
UniProt Gene Name
ZIC1
UniProt Synonym Gene Names
ZIC; ZNF201
UniProt Entry Name
ZIC1_HUMAN
NCBI Description
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]
Research Articles on Zic1/2/3
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Product Notes
The Zic1/2/3 zic1 (Catalog #AAA3002642) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Zic1/2/3 (D348) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Zic1/2/3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the Zic1/2/3 zic1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Zic1/2/3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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