Western Blot (WB)
(Western blot analysis of ZHX2 using Jurkat whole cell lysates)
Rabbit anti-Human, Mouse ZHX2 Polyclonal Antibody | anti-ZHX2 antibody
ZHX2 Antibody
Gene Names
ZHX2; RAF; AFR1
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ZHX2; Polyclonal Antibody; ZHX2 Antibody; AFP regulator 1; AFR1; Alpha fetoprotein regulator 1; Alpha-fetoprotein regulator 1; KIAA0854; RAF; Regulator of AFP; Transcription factor ZHX2; ZHX2_HUMAN; Zinc finger and homeodomain protein 2; Zinc fingers and homeoboxes 2; Zinc fingers and homeoboxes protein 2; anti-ZHX2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
ZHX2 antibody detects endogenous levels of total ZHX2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
837
Applicable Applications for anti-ZHX2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human ZHX2
Subcellular Location
Nucleus.
Tissue Specificity
Ubiquitously expressed. Expressed in podocytes.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Pig (100%), Bovine (92%), Horse (83%), Sheep (92%), Rabbit (83%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of ZHX2 using Jurkat whole cell lysates)
Western Blot (WB)
(Western blot analysis of ZHX2 using Jurkat whole cell lysates)
Related Product Information for anti-ZHX2 antibody
Function: Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.
Subunit Structure: Forms a homodimer (via homeobox domain). Forms a heterodimer with ZHX1 (via HD1 domain). Forms a heterodimer with ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts (via homeobox domain) with NFYA (via N-terminus).
Similarity: Belongs to the ZHX family.
Subunit Structure: Forms a homodimer (via homeobox domain). Forms a heterodimer with ZHX1 (via HD1 domain). Forms a heterodimer with ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts (via homeobox domain) with NFYA (via N-terminus).
Similarity: Belongs to the ZHX family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 92 kDa
Predicted: 93 kDa
Predicted: 93 kDa
NCBI Official Full Name
zinc fingers and homeoboxes protein 2
NCBI Official Synonym Full Names
zinc fingers and homeoboxes 2
NCBI Official Symbol
ZHX2
NCBI Official Synonym Symbols
RAF; AFR1
NCBI Protein Information
zinc fingers and homeoboxes protein 2
UniProt Protein Name
Zinc fingers and homeoboxes protein 2
Protein Family
UniProt Gene Name
ZHX2
UniProt Synonym Gene Names
AFR1; KIAA0854; RAF; AFP regulator 1
NCBI Description
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]
Uniprot Description
Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.
Research Articles on ZHX2
Similar Products
Product Notes
The ZHX2 zhx2 (Catalog #AAA9609216) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZHX2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZHX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the ZHX2 zhx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZHX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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